352431-55-1 Usage
Description
1-CHLOROADAMANTANE-D15 is an isotope-labeled analog of 1-Chloroadamantane, which is an adamantane derivative. It is characterized by its virucidal activity and is used in various applications due to its unique properties.
Uses
Used in Pharmaceutical Industry:
1-CHLOROADAMANTANE-D15 is used as a virucidal agent for its ability to exhibit virucidal activity against the Newcastle disease virus in chick embryo fibroblasts. This makes it a promising candidate for the development of antiviral treatments and therapies.
Used in Research and Development:
1-CHLOROADAMANTANE-D15 serves as a valuable tool in research and development due to its isotope-labeled nature. It can be utilized in studying the mechanisms of viral infections and the effectiveness of potential antiviral compounds, contributing to the advancement of medical knowledge and the development of new treatments.
Used in Virology Studies:
In the field of virology, 1-CHLOROADAMANTANE-D15 is used as a research compound to better understand the interactions between viruses and potential antiviral agents. This knowledge can be applied to the development of new strategies for combating viral diseases and improving public health.
Check Digit Verification of cas no
The CAS Registry Mumber 352431-55-1 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 3,5,2,4,3 and 1 respectively; the second part has 2 digits, 5 and 5 respectively.
Calculate Digit Verification of CAS Registry Number 352431-55:
(8*3)+(7*5)+(6*2)+(5*4)+(4*3)+(3*1)+(2*5)+(1*5)=121
121 % 10 = 1
So 352431-55-1 is a valid CAS Registry Number.
352431-55-1Relevant articles and documents
Mechanism of Hydrocarbon Functionalization by an Iodate/Chloride System: The Role of Ester Protection
Schwartz, Nichole A.,Boaz, Nicholas C.,Kalman, Steven E.,Zhuang, Thompson,Goldberg, Jonathan M.,Fu, Ross,Nielsen, Robert J.,Goddard, William A.,Groves, John T.,Gunnoe, T. Brent
, p. 3138 - 3149 (2018)
Mixtures of chloride and iodate salts for light alkane oxidation achieve >20% yield of methyl trifluoroacetate (TFA) from methane with >85% selectivity. The mechanism of this C-H oxygenation has been probed by examining adamantane as a model substrate. These recent results lend support to the involvement of free radicals. Comparative studies between radical chlorination and iodate/chloride functionalization of adamantane afford statistically identical 3°:2° selectivities (～5.2:1) and kinetic isotope effects for C-H/C-D functionalization (kH/kD = 1.6(3), 1.52(3)). Alkane functionalization by iodate/chloride in HTFA is proposed to occur through H-atom abstraction by free radical species including Cl? to give alkyl radicals. Iodine, which forms by in situ reduction of iodate, traps alkyl radicals as alkyl iodides that are subsequently converted to alkyl esters in HTFA solvent. Importantly, the alkyl ester products (RTFA) are quite stable to further oxidation under the oxidizing conditions due to the protecting nature of the ester moiety.
