352528-33-7

Basic information

• Product Name: 1-(6-ethoxycarbonyl-2-benzothiazolyl)-3-ethylurea
• Synonyms: 1-(6-ethoxycarbonyl-2-benzothiazolyl)-3-ethylurea
• CAS NO: 352528-33-7
• Molecular Weight: 293.346
• Mol File: 352528-33-7.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 1-(6-ethoxycarbonyl-2-benzothiazolyl)-3-ethylurea(CAS DataBase Reference)
• NIST Chemistry Reference: 1-(6-ethoxycarbonyl-2-benzothiazolyl)-3-ethylurea(352528-33-7)
• EPA Substance Registry System: 1-(6-ethoxycarbonyl-2-benzothiazolyl)-3-ethylurea(352528-33-7)

Safety Data

• Hazardous Substances Data: 352528-33-7(Hazardous Substances Data)

Upstream product

• 50850-93-6 ethyl 2-aminobenzothiazole-6-carboxylate 
• 109-90-0 ethyl isocyanate 

Downstream Products

• 1024583-67-2 2-(3-ethyl-ureido)-benzothiazole-6-carboxylic acid [2-methyl-5-(3-methyl-benzoylamino)-phenyl]-amide 
• 1024583-35-4 (3-{[2-(3-ethyl-ureido)-benzothiazole-6-carbonyl]-amino}-4-methyl-phenyl)-carbamic acid tert-butyl ester 
• 1024583-36-5 2-(3-ethyl-ureido)-benzothiazole-6-carboxylic acid (5-amino-2-methyl-phenyl)-amide 

Relevant articles and documents

Benzothiazole derivatives

The present invention is directed to a compound of formula (I), racemic-diastereomeric mixtures thereof, optical isomers thereof, prodrugs thereof, isotopes thereof or pharmaceutically-acceptable salts of said compound, isomers, prodrugs and isotopes, wherein the variables are defined herein. The compounds of this invention are useful as inhibitors of serine/threonine and tyrosine kinases. In particular, compounds of this invention are useful as inhibitors of tyrosine kinases that are important in hyperproliferative diseases, especially in cancer and in the process of angiogenesis.