35288-44-9

Basic information

• Product Name: 4-Propoxy-3-nitrobenzoic acid
• Synonyms: 4-Propoxy-3-nitrobenzoic acid;3-NITRO-4-PROPOXYBENZOIC ACID
• CAS NO: 35288-44-9
• Molecular Formula: C₁₀H₁₁NO₅
• Molecular Weight: 225.2
• Mol File: 35288-44-9.mol
• Article Data: 8

Chemical Properties

• Melting Point: 167.5-169.7 °C
• Boiling Point: 387.3 °C at 760 mmHg
• Flash Point: 188 °C
• Appearance: /
• Density: 1.318 g/cm³
• Vapor Pressure: 1.08E-06mmHg at 25°C
• Refractive Index: 1.565
• PKA: 3.85±0.10(Predicted)
• CAS DataBase Reference: 4-Propoxy-3-nitrobenzoic acid(CAS DataBase Reference)
• NIST Chemistry Reference: 4-Propoxy-3-nitrobenzoic acid(35288-44-9)
• EPA Substance Registry System: 4-Propoxy-3-nitrobenzoic acid(35288-44-9)

Safety Data

• Hazardous Substances Data: 35288-44-9(Hazardous Substances Data)

Usage

General Description

4-Propoxy-3-nitrobenzoic acid is a chemical compound with the molecular formula C10H9NO5. It is a yellow solid with a molecular weight of 223.18 g/mol. This chemical is commonly used in organic synthesis and pharmaceutical research as a building block for various drugs and biologically active compounds. It is also utilized as a precursor in the production of dyes and pigments. 4-Propoxy-3-nitrobenzoic acid is known to be harmful if ingested or inhaled, and may cause skin and eye irritation upon contact. It should be handled and stored with proper safety precautions to prevent any potential health risks.

InChI:InChI=1/C10H11NO5/c1-2-5-16-9-4-3-7(10(12)13)6-8(9)11(14)15/h3-4,6H,2,5H2,1H3,(H,12,13)

Upstream product

• 1221258-88-3 3-nitro-4-propoxybenzoic acid propyl ester 
• 59691-12-2 methyl 3-nitro-4-propoxybenzoate 
• 616-82-0 3-nitro-4-hydroxybenzoic acid 
• 599-91-7 propyl tosylate 

Downstream Products

• 59691-15-5 3-amino-4-propoxybenzoic acid 
• 499-67-2 Proparacain 
• 736870-51-2 3-nitro-4-propoxy-benzoic acid-(2-diethylamino-ethyl ester) 

Relevant articles and documents

N-(3-nitro-4-alkoxybenzoyl)amino acid compounds as well as preparation method and application thereof

The invention discloses N-(3-nitro-4-alkoxybenzoyl)amino acid compounds as well as a preparation method and an application thereof and belongs to the field of medicines. 4-hydroxy-3-nitrobenzoic acidis subjected to methanol esterification, bromo-alkane substitution, hydrolysis and chlorination and then acylated with L-phenylglycine, R2 which is L-phenylglycine sodium salt is obtained, and the N-(3-nitro-4-alkoxybenzoyl)amino acid compounds are obtained after hydrolysis. The N-(3-nitro-4-alkoxybenzoyl)amino acid compounds have novel chemical structures, have good effects in an in-vitro xanthine oxidase inhibition activity test and can be used for treating and preventing gout diseases.

S1P RECEPTORS MODULATORS AND THEIR USE THEREOF

The invention relates to novel compounds that have S1P receptor modulating activity. Further, the invention relates to a pharmaceutical comprising at least one compound of the invention for the treatment of diseases and/or conditions caused by or associated with inappropriate S1P receptor modulating activity or expression, for example, autoimmune response. A further aspect of the invention relates to the use of a pharmaceutical comprising at least one compound of the invention for the manufacture of a medicament for the treatment of diseases and/or conditions caused by or associated with inappropriate S1P receptor modulating activity or expression such as autoimmune response.