3535-30-6

Basic information

• Product Name: 4-ETHOXY-3-METHOXY-BENZOIC ACID
• Synonyms: 4-ETHOXY-3-METHOXY-BENZOIC ACID;AKOS 214-34;RARECHEM AL BE 0255;4-ethoxy-m-anisic acid;benzoic acid, 4-ethoxy-3-methoxy-;Einecs 222-567-5;4-ethoxy-3-methoxybenzoic acid(SALTDATA: FREE);Etobenzanid metabolite (4-Ethoxymethoxy benzoic acid)
• CAS NO: 3535-30-6
• Molecular Formula: C₁₀H₁₂O₄
• Molecular Weight: 196.2
• EINECS: 222-567-5
• Mol File: 3535-30-6.mol
• Article Data: 12

Chemical Properties

• Boiling Point: 316.4 °C at 760 mmHg
• Flash Point: 123 °C
• Appearance: /
• Density: 1.178 g/cm³
• Vapor Pressure: 0.000173mmHg at 25°C
• CAS DataBase Reference: 4-ETHOXY-3-METHOXY-BENZOIC ACID(CAS DataBase Reference)
• NIST Chemistry Reference: 4-ETHOXY-3-METHOXY-BENZOIC ACID(3535-30-6)
• EPA Substance Registry System: 4-ETHOXY-3-METHOXY-BENZOIC ACID(3535-30-6)

Safety Data

• HazardClass: IRRITANT
• Hazardous Substances Data: 3535-30-6(Hazardous Substances Data)

Usage

Uses

4-Ethoxy-3-methoxybenzoic acid

InChI:InChI=1/C10H12O4/c1-3-14-8-5-4-7(10(11)12)6-9(8)13-2/h4-6H,3H2,1-2H3,(H,11,12)/p-1

Upstream product

• 120-25-2 4-ethoxy-3-methoxybenzaldehyde 
• 71-43-2 benzene 
• 1117-96-0 Diazoethan 
• 121-34-6 3-methoxy-4-hydroxybenzoic acid 
• 7784-67-0 ethyl isoeugenol 
• 458-37-7 curcumin 
• 74368-00-6 4-allyl-1-ethoxy-2-methoxybenzene 
• 3535-24-8 4-ethoxy-3-methoxybenzoic acid methyl ester 
• 3943-74-6 4-hydroxy-3-methoxybenzoic acid methyl ester 
• 203312-21-4 1-(4-ethoxy-3-methoxyphenyl)-2-(2-methoxy-phenoxy)propan-1,3-diol 
• 1320357-66-1 O-(4-ethoxy-3-methoxybenzoyl)-N-phenyl-acetohydroxamic acid 
• 3535-36-2 4-ethoxy-3-methoxybenzoil chloride 
• 97-53-0 4-allylguaiacol 
• 96894-13-2 (+)-1-acetoxypinoresinol 

Downstream Products

• 3535-24-8 4-ethoxy-3-methoxybenzoic acid methyl ester 
• 99-50-3 3,4-Dihydroxybenzoic acid 
• 75-03-6 ethyl iodide 
• 74-88-4 methyl iodide 
• 53293-05-3 Ethyl p-ethoxy-m-methoxybenzoylacetate 
• 854677-96-6 4-(4-ethoxy-3-methoxy-phenyl)-4-oxo-butyric acid 
• 247568-34-9 2-fluoro-5-nitro-N-(1,3-benzodioxol-5-ylmethyl)benzamide 
• 247566-96-7 2-(tert-Butylamino)-5-nitro-N-(1,3-benzodioxol-5-ylmethyl)benzamide 
• 247567-01-7 2-(tert-Butoxyamino)-5-nitro-N-(1,3-benzodioxol-5-ylmethyl)benzamide 
• 247566-86-5 (R)-2-(2-Hydroxy-1-methylethylamino)-5-nitro-N-(1,3-benzodioxol-5-ylmethyl)benzamide 
• 247566-87-6 5-Nitro-N-(1,3-benzodioxol-5-ylmethyl)-2-(2-thiazolylamino)benzamide 
• 247566-83-2 (S)-2-(1-carboxyethylamino)-5-nitro-N-(1,3-benzodioxol-5-ylmethyl)benzamide 
• 247566-85-4 2-(2-Hydroxy-1,1-dimethylethylamino)-5-nitro-N-(1,3-benzodioxol-5-ylmethyl)benzamide 
• 247568-38-3 2-[2-Chloro-1-(chloromethyl)ethylamino]-5-nitro-N-(1,3-benzodioxol-5-ylmethyl)benzamide 

Relevant articles and documents

VU6010608, a Novel mGlu7 NAM from a Series of N-(2-(1H-1,2,4-Triazol-1-yl)-5-(trifluoromethoxy)phenyl)benzamides

Herein, we report the structure-activity relationships within a series of mGlu7 NAMs based on an N-(2-(1H-1,2,4-triazol-1-yl)-5-(trifluoromethoxy)phenyl)benzamide core with excellent CNS penetration (Kp 1.9-5.8 and Kp,uu 0.4-1.4). Analogues in this series displayed steep SAR. Of these, VU6010608 (11a) emerged with robust efficacy in blocking high frequency stimulated long-term potentiation in electrophysiology studies.

SELECTIVE CARBON-CARBON BOND CLEAVAGE BY EARTH ABUNDANT VANADIUM COMPOUNDS UNDER VISIBLE LIGHT PHOTOCATALYSIS

Provided herein a vanadium(V) complex of formula I, where R1 to R8 are as defined herein. Also provided herein are reactions making use of the vanadium(V) complex of formula I, such as selective sp3-sp3 carbon-carbon bond cleavage under visible light photocatalysis and photodegradation of lignin.

Photoacid generators (PAGs) based on N-acyl-N-phenylhydroxylamines for carboxylic and sulfonic acids

Simple and efficient photoacid generators (PAGs) for carboxylic and sulfonic acids based on N-acyl-N-phenylhydroxylamines have been demonstrated. Irradiation of o-carboxylates and thermally rearranged o-arenesulfonates of N-acyl-N-phenylhydroxylamines using UV light (≥254 nm) in aqueous methanolic solution resulted in efficient generation of carboxylic and sulfonic acids, respectively. The carboxylic acid generation ability of N-acyl-N- phenylhydroxylamines was found to be dependent on their N-acyl substituents. Further, polymer bearing o-arenesulfonates of N-acyl-N-phenylhydroxylamine was synthesized and demonstrated as PAG for sulfonic acids.