35405-94-8

Basic information

• Product Name: ethyl 4H-furo[3,2-b]pyrrole-5-carboxylate
• Synonyms: ethyl 4H-furo[3,2-b]pyrrole-5-carboxylate
• CAS NO: 35405-94-8
• Molecular Formula: C₉H₉NO₃
• Molecular Weight: 179.18
• Mol File: 35405-94-8.mol
• Article Data: 15

Chemical Properties

• Boiling Point: 298.307 °C at 760 mmHg
• Flash Point: 134.212 °C
• Appearance: /
• Density: 1.288 g/cm³
• CAS DataBase Reference: ethyl 4H-furo[3,2-b]pyrrole-5-carboxylate(CAS DataBase Reference)
• NIST Chemistry Reference: ethyl 4H-furo[3,2-b]pyrrole-5-carboxylate(35405-94-8)
• EPA Substance Registry System: ethyl 4H-furo[3,2-b]pyrrole-5-carboxylate(35405-94-8)

Safety Data

• Hazardous Substances Data: 35405-94-8(Hazardous Substances Data)

Usage

Synthesis Reference(s)

Canadian Journal of Chemistry, 56, p. 1429, 1978 DOI: 10.1139/v78-234

Upstream product

• 71754-74-0 ethyl 2-azidopropanoate 
• 98-01-1 furfural 
• 1501968-64-4 ethyl 4-benzoyl-4H-furo[3,2-b]pyrrole-5-carboxylate 
• 14757-78-9 3-bromofurfural 
• 1501968-56-4 C₁₆H₁₆BrNO₆ 
• 35355-49-8 ethyl 2-azido-3-(furan-2-yl)acrylate 

Downstream Products

• 144658-77-5 4-(2-Nitro-benzyl)-4H-furo[3,2-b]pyrrole-5-carboxylic acid ethyl ester 
• 144658-76-4 4-(4-Nitro-benzyl)-4H-furo[3,2-b]pyrrole-5-carboxylic acid ethyl ester 
• 1309794-53-3 ethyl 4-(benzoyloxymethyl)-4H-furo[3,2-b]pyrrole-5-carboxylate 
• 117613-30-6 4-methylfuro[3,2-b]pyrrole-5-carboxylic acid 
• 250-91-9 furo<3,2-b>pyrrole 
• 80564-03-0 C₂₃H₁₈N₂O₅ 
• 80709-74-6 4-Ethylfuro<3,2-b>pyrrole-5-carboxylic acid 
• 144658-72-0 4-benzylfuro<3,2-b>pyrrole-5-carboxylic acid 
• 119118-10-4 4-benzylfuro<3,2-b>pyrrole 
• 132120-25-3 ethyl 4-benzylfuro<3,2-b>pyrrole-5-carboxylate 
• 80564-00-7 (3R,7bS)-3-Benzoyl-2-phenyl-3,3a,7,7b-tetrahydro-2H-pyrrolo[2',3':4,5]furo[2,3-d]isoxazole-6-carboxylic acid ethyl ester 
• 67268-37-5 4H-furo[3,2-b]pyrrole-5-carboxylic acid 

Relevant articles and documents

The effect of single atom replacement on organic thin film transistors: Case of thieno[3,2-b] pyrrole vs. furo[3,2-b] pyrrole

Despite polypyrrole having higher conductivities compared to polythiophenes, pyrrole based materials have garnered less attention in the organic electronics community due to their instability in air. Construction of stable pyrrolic units could be achieved by fusing relatively unstable pyrrole with stable aromatic rings. In this report, we discuss and compare the organic field-effect transistor performances of the smallest S,N-heteroacene and O,N-heteroacene, thieno[3,2-b]pyrrole and furo[3,2-b]pyrrole, respectively, in donor-acceptor-donor type organic semiconducting small molecules. Since both building blocks are highly electron-rich, thiophene flanked 5,6-difluorobenzo[c][1,2,5]thiadiazole is employed as a central electron-withdrawing unit. The small molecule containing thieno[3,2-b]pyrrole exhibit moderate hole mobilities (10-3 cm2 V-1 s-1) irrespective of the annealing temperature. In contrast, the small molecule bearing furo[3,2-b]pyrrole is completely inactive in field-effect transistors. To the best of our knowledge this is the first report to compare the smallest units of S,N and O,N-heteroacenes for organic field-effect transistors.

TREATMENT OF VIRAL INFECTIONS WITH COMBINATION OF PIKFYVE KINASE INHIBITORS AND TMPRSS-2 INHIBITORS

The present invention relates to methods of treating viral infections including COVID-19 and compositions with a combination of (i) an inhibitor of phosphatidylinositol-3-phosphate 5-kinase (PIKfyve) and (ii) an inhibitor of transmembrane serine proteinase 2 (TMPRSS-2).

D-AMINO ACID OXIDASE INHIBITORS AND THERAPEUTIC USES THEREOF

The present invention relates to compounds of Formula (I): or a pharmaceutically acceptable salt thereof, wherein: each of A, B, C, D, and E, independently, is C, N, N—H, O, S, or absent is a single bond or a double bond; each of X, Y, and Z, independentl