354153-64-3 Usage
Description
(R)-b-Amino-4-bromo-benzeneethanol is a chiral chemical compound belonging to the class of benzeneethanols. It features a bromine atom attached to the benzene ring and an amino group attached to the ethanol moiety, giving it a specific orientation in its structure. (R)-b-AMino-4-broMo-benzeneethanol is widely utilized in organic synthesis and pharmaceutical research due to its potential applications in the development of new drugs and biologically active molecules. The chiral nature of (R)-b-Amino-4-bromo-benzeneethanol makes it a crucial intermediate in the synthesis of chiral drugs and pharmaceuticals, while its unique structure and properties contribute to its value as a building block in organic chemistry.
Uses
Used in Pharmaceutical Research:
(R)-b-Amino-4-bromo-benzeneethanol is used as a key intermediate for the development of new drugs and biologically active molecules. Its unique structure and chiral nature allow for the creation of various pharmaceutical compounds with potential therapeutic applications.
Used in Organic Synthesis:
(R)-b-Amino-4-bromo-benzeneethanol serves as a valuable building block in the field of organic chemistry. Its specific orientation and functional groups enable the synthesis of a wide range of organic compounds, contributing to the advancement of chemical research and development.
Used in Chiral Drug Synthesis:
Due to its chiral nature, (R)-b-Amino-4-bromo-benzeneethanol is used as an essential intermediate in the synthesis of chiral drugs. (R)-b-AMino-4-broMo-benzeneethanol's specific orientation allows for the creation of enantiomerically pure pharmaceuticals, which is crucial for ensuring the desired therapeutic effects and minimizing potential side effects.
Used in the Chemical Industry:
(R)-b-Amino-4-bromo-benzeneethanol is employed in the chemical industry for the production of various specialty chemicals and materials. Its unique structure and properties make it a versatile building block for the development of new products with specific applications in areas such as coatings, adhesives, and polymers.
Check Digit Verification of cas no
The CAS Registry Mumber 354153-64-3 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 3,5,4,1,5 and 3 respectively; the second part has 2 digits, 6 and 4 respectively.
Calculate Digit Verification of CAS Registry Number 354153-64:
(8*3)+(7*5)+(6*4)+(5*1)+(4*5)+(3*3)+(2*6)+(1*4)=133
133 % 10 = 3
So 354153-64-3 is a valid CAS Registry Number.
354153-64-3Relevant articles and documents
Synthesis of enantiopure 1,2-azido and 1,2-amino alcohols via regio- and stereoselective ring-opening of enantiopure epoxides by sodium azide in hot water
Wang, Hai-Yang,Huang, Kun,De Jesús, Melvin,Espinosa, Sandraliz,Pi?ero-Santiago, Luis E.,Barnes, Charles L.,Ortiz-Marciales, Margarita
, p. 91 - 100 (2016/02/09)
A practical and convenient method for the efficient and regio- and stereoselective ring-opening of enantiopure monosubstituted epoxides by sodium azide under hydrolytic conditions is reported. The ring-opening of enantiopure styryl and pyridyl (S)-epoxides by N3- in hot water takes place preferentially at the internal position with complete inversion of configuration to produce (R)-2-azido ethanols with up to 99% enantio- and regioselectivity, while the (S)-adamantyl oxirane provides mainly the (S)-1-adamantyl-2-azido ethanol in excellent yield. In general, 1,2-amino ethanols were obtained in high yield and excellent enantiopurity by the reduction of the chiral 1,2-azido ethanols with PPh3 in water/THF, and then converted into the Boc or acetamide derivatives.
An effective and useful synthesis of enantiomerically enriched arylglycinols
Bandini, Marco,Cozzi, Pier Giorgio,Gazzano, Massimo,Umani-Ronchi, Achille
, p. 1937 - 1942 (2007/10/03)
A two-step synthesis of racemic arylglycinols, together with a simple and straightforward methodology for their resolution, is described. This method constitutes a practical means of preparing racemic and optically pure electron-rich or electron-poor subs
