35445-32-0

Basic information

• Product Name: 1,4-dimethyl-5-carbethoxyimidazole
• Synonyms: 1,4-dimethyl-5-carbethoxyimidazole;EOS-62089
• CAS NO: 35445-32-0
• Molecular Formula: C8H12N2O2
• Molecular Weight: 168.19308
• Mol File: 35445-32-0.mol
• Article Data: 9

Chemical Properties

• Boiling Point: 102-103 °C(Press: 0.2 Torr)
• Appearance: /
• Density: 1.12±0.1 g/cm3(Predicted)
• Storage Temp.: Sealed in dry,Room Temperature
• PKA: 4.88±0.61(Predicted)
• CAS DataBase Reference: 1,4-dimethyl-5-carbethoxyimidazole(CAS DataBase Reference)
• NIST Chemistry Reference: 1,4-dimethyl-5-carbethoxyimidazole(35445-32-0)
• EPA Substance Registry System: 1,4-dimethyl-5-carbethoxyimidazole(35445-32-0)

Safety Data

• Hazardous Substances Data: 35445-32-0(Hazardous Substances Data)

Usage

General Description

1,4-dimethyl-5-carbethoxyimidazole is a chemical compound that belongs to the imidazole group. It is a derivative of imidazole with two methyl groups and a carbethoxy group attached to the nitrogen atom. 1,4-dimethyl-5-carbethoxyimidazole is commonly used as a building block in the synthesis of pharmaceuticals and agrochemicals, as well as in the production of dyes, pigments, and other organic compounds. It has also been studied for its potential as an anti-cancer and anti-inflammatory agent. Additionally, 1,4-dimethyl-5-carbethoxyimidazole has been found to possess anti-microbial and anti-fungal properties, making it useful in the development of antimicrobial agents. Overall, this compound has a wide range of potential applications in various industries and has been the subject of ongoing research for its diverse biological activities.

Upstream product

• 51605-32-4 ethyl 4⁽⁵⁾-methylimidazole-5⁽⁴⁾-carboxylate 
• 74-88-4 methyl iodide 
• 67-56-1 methanol 
• 51605-32-4 Ethyl 5-Methyl-4-imidazolecarboxylate 

Downstream Products

• 1094342-63-8 3-chloro-5-[(6-chloro-3-{[5-(1,4-dimethyl-1H-imidazol-5-yl)-1,3,4-oxadiazol-2-yl]methyl}-2-fluorophenyl)oxy]benzonitrile 
• 1094346-39-0 1,4-dimethyl-1H-imidazole-5-carbohydrazide 
• 78449-67-9 3,5-dimethyl-3H-imidazole-4-carboxylic acid 
• 113444-43-2 ethyl 2-bromo-1,4-dimethyl-1H-imidazole-5-carboxylate 

Relevant articles and documents

Carbon-13 Nuclear Magnetic Resonance as a Probe for the Structural Assignment of 1,4,5-Trisubstituted Imidazoles

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Discovery of LY3325656: A GPR142 agonist suitable for clinical testing in human

The discovery and optimization of a novel series of GPR142 agonists are described. These led to the identification of compound 21 (LY3325656), which demonstrated anti-diabetic benefits in pre-clinical studies and ADME/PK properties suitable for human dosing. Compound 21 is the first GPR142 agonist molecule advancing to phase 1 clinic trials for the treatment of Type 2 diabetes.

CHEMICAL COMPOUNDS

The present invention relates to compounds that are a non-nucleoside reverse transcriptase inhibitors, and to processes for the preparation and use of the same. Specifically, the present invention includes methods of using such compounds in the treatment of human immunodeficiency virus infection.