35480-31-0 Usage
Description
METHYL 2,5-BIS(2,2,2-TRIFLUOROETHOXY)BENZOATE is a chemical compound that serves as an intermediate in the synthesis of Flecainide-d4 (F390003), which is the isotope labeled analog of Flecainide. Flecainide is an antiarrhythmic drug belonging to class IC, used to treat abnormal heart rhythms.
Uses
Used in Pharmaceutical Industry:
METHYL 2,5-BIS(2,2,2-TRIFLUOROETHOXY)BENZOATE is used as a key intermediate in the synthesis of Flecainide-d4, an isotope labeled analog of the antiarrhythmic drug Flecainide. METHYL 2,5-BIS(2,2,2-TRIFLUOROETHOXY)BENZOATE plays a crucial role in the development and production of Flecainide-d4, which is utilized for research purposes in understanding the mechanism of action and pharmacokinetics of Flecainide.
Check Digit Verification of cas no
The CAS Registry Mumber 35480-31-0 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 3,5,4,8 and 0 respectively; the second part has 2 digits, 3 and 1 respectively.
Calculate Digit Verification of CAS Registry Number 35480-31:
(7*3)+(6*5)+(5*4)+(4*8)+(3*0)+(2*3)+(1*1)=110
110 % 10 = 0
So 35480-31-0 is a valid CAS Registry Number.
InChI:InChI=1/C12H10F6O4/c1-20-10(19)8-4-7(21-5-11(13,14)15)2-3-9(8)22-6-12(16,17)18/h2-4H,5-6H2,1H3
35480-31-0Relevant articles and documents
Synthesis of novel 5-(2,5-bis(2,2,2-trifluoroethoxy)phenyl)-1,3,4-oxadiazole-2-thiol derivatives as potential glucosidase inhibitors
Gani, Ramesh S.,Kudva, Avinash K.,Timanagouda, Karabasanagouda,Raghuveer,Mujawar, Salma Begum Hussain,Joshi, Shrinivas D.,Raghu, Shamprasad Varija
, (2021)
Background: A hybrid molecule of different biologically active substances can improve affinity and efficiency compared to a standard drug. Hence based on this fact, we predict that a combination of fluorine, oxadiazole, sulfur, etc., may enhance α-glucosi
Novel process for the preparation of flecainide, its pharmaceutically acceptable salts and important intermediates thereof
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Page/Page column 4, (2010/02/11)
Process for the preparation of Flecainide, its pharmaceutically acceptable salts and important intermediates thereof that involves the use of the 2-halobenzoic acid and its derivatives as a starting material. The use of this process also allows for the synthesis of a novel intermediate useful in the production of Flecainide. This new process is an inexpensive and efficient process for the manufacture of these compounds.
