35488-10-9

Basic information

• Product Name: 4-Pyridinamine, N-(4-methylphenyl)-
• Synonyms: pyridin-4-yl-p-tolyl-amine
• CAS NO: 35488-10-9
• Molecular Formula: C12H12N2
• Molecular Weight: 184.241
• Mol File: 35488-10-9.mol
• Article Data: 4

Chemical Properties

• Melting Point: 198 °C
• Boiling Point: 342.6±17.0 °C(Predicted)
• Density: 1.116±0.06 g/cm3(Predicted)
• CAS DataBase Reference: 4-Pyridinamine, N-(4-methylphenyl)-(CAS DataBase Reference)
• NIST Chemistry Reference: 4-Pyridinamine, N-(4-methylphenyl)-(35488-10-9)
• EPA Substance Registry System: 4-Pyridinamine, N-(4-methylphenyl)-(35488-10-9)

Safety Data

• Hazardous Substances Data: 35488-10-9(Hazardous Substances Data)

Upstream product

• 540-23-8 p-toluidine hydrochloride 
• 5421-92-1 1-(4-pyridyl)pyridinium chloride hydrochloride 
• 1412913-70-2 5-methyl-1-(4-pyridyl)-1H-1,2,3-benzotriazole 
• 64858-67-9 1-(4-methylphenyl)-1H-1,2,3-triazolo[4,5-c]pyridine 
• 626-64-2 pyridin-4-ol 
• 5435-54-1 4-hydroxy-3-nitropyridine 
• 13091-23-1 4-chloro-3-nitropyridine 
• 54696-69-4 4-(4-methylphenyl)amino-3-nitropyridine 
• 1412913-71-3 4-methyl-N¹-(pyridin-4-yl)benzene-1,2-diamine 
• 1038315-36-4 3-amino-4-(4-methylphenyl)aminopyridine 
• 106-49-0 p-toluidine 
• 504-24-5 4-aminopyridine 

Downstream Products

• 1412913-72-4 4-(4-methyl-2,6-dinitrophenyl)aminopyridine 
• 1412913-71-3 4-methyl-N¹-(pyridin-4-yl)benzene-1,2-diamine 

Relevant articles and documents

Selective Functionalization of Aminoheterocycles by a Pyrylium Salt

The functionalization of aminoheterocycles by using a pyrylium tetrafluoroborate reagent (Pyry-BF4) is presented. This reagent efficiently condenses with a great variety of heterocyclic amines and primes the C?N bond for nucleophilic aromatic substitution. More than 60 examples for the formation of C?O, C?N, C?S, or C?SO2R bonds are disclosed herein. In contrast to C?N activation through diazotization and polyalkylation, this method is characterized by its mild conditions and impressive functional-group tolerance. In addition to small-molecule derivatization, Pyry-BF4 allows the introduction of functional groups in a late-stage fashion to furnish highly functionalized structures.

Method of Treating Senile Cognitive Decline with N'-substituted Aminopyridine Adrenergic Agents

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