35508-99-7

Basic information

• Product Name: β-dimethylamino-N-phenylpropionic acid amide
• Synonyms: β-dimethylamino-N-phenylpropionic acid amide
• CAS NO: 35508-99-7
• Molecular Weight: 192.261
• Mol File: 35508-99-7.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: β-dimethylamino-N-phenylpropionic acid amide(CAS DataBase Reference)
• NIST Chemistry Reference: β-dimethylamino-N-phenylpropionic acid amide(35508-99-7)
• EPA Substance Registry System: β-dimethylamino-N-phenylpropionic acid amide(35508-99-7)

Safety Data

• Hazardous Substances Data: 35508-99-7(Hazardous Substances Data)

Upstream product

• 124-40-3 dimethyl amine 
• 3853-06-3 methyl 3-(dimethylamino)propionate 
• 62-53-3 aniline 
• 3460-04-6 3-chloro-N-phenylpropionamide 

Downstream Products

• 13658-95-2 N¹,N¹-dimethyl-N³-phenylpropane-1,3-diamine 

Relevant articles and documents

LiCl-promoted amination of β-methoxy amides (γ-lactones)

An efficient and mild method has been developed for the amination of β-methoxy amides (γ-lactones) including natural products michelolide, costunolide and parthenolide derivatives by using lithium chloride in good yields. This reaction is applicable to a wide range of substrates with good functional group tolerance. Mechanism studies show that the reactions undergo a LiCl promoted MeOH elimination from the substrates to form the corresponding α,β-unsaturated intermediates followed by the Michael addition of amines.