35512-31-3

Basic information

• Product Name: 4-(1H-IMIDAZOL-4-YL)PHENYL METHYL ETHER
• Synonyms: 4-(4-METHOXYPHENYL)-1H-IMIDAZOLE;4-(1H-IMIDAZOL-4-YL)PHENYL METHYL ETHER
• CAS NO: 35512-31-3
• Molecular Formula: C₁₀H₁₀N₂O
• Molecular Weight: 174.2
• Mol File: 35512-31-3.mol
• Article Data: 20

Chemical Properties

• Appearance: /
• CAS DataBase Reference: 4-(1H-IMIDAZOL-4-YL)PHENYL METHYL ETHER(CAS DataBase Reference)
• NIST Chemistry Reference: 4-(1H-IMIDAZOL-4-YL)PHENYL METHYL ETHER(35512-31-3)
• EPA Substance Registry System: 4-(1H-IMIDAZOL-4-YL)PHENYL METHYL ETHER(35512-31-3)

Safety Data

• Hazardous Substances Data: 35512-31-3(Hazardous Substances Data)

Upstream product

• 1029684-38-5 5-(4-methoxyphenyl)-1-(tetrahydro-2H-pyran-2-yl)-1H-imidazole 
• 849590-39-2 (±)-N-(4-methoxybenzylidene)-2-methylpropane-2-sulfinamide 
• 38622-91-2 [(p-methylphenyl)sulfonylmethyl]isonitrile 
• 5720-07-0 4-methoxyphenylboronic acid 
• 2302-25-2 5-bromo-1H-imidazole 
• 1041845-36-6 1-benzyl-5-(4-methoxyphenyl)-1H-imidazole 
• 89108-47-4 4-diazo-4H-imidazole 
• 100-66-3 methoxybenzene 
• 50-00-0 formaldehyd 
• 67-56-1 methanol 
• 768-60-5 4-methoxyphenylacetylen 
• 2632-13-5 2-Bromo-4'-methoxyacetophenone 
• 123-11-5 4-methoxy-benzaldehyde 
• 2302-25-2 4-bromo-1 H-imidazole 

Downstream Products

• 875155-39-8 5-[4-(4-methoxy-phenyl)-imidazol-1-yl]-2-nitro-4-trifluoromethyl-benzoic acid methyl ester 
• 367262-73-5 1,4-bis-(4-methoxyphenyl)-1H-imidazole 
• 1356960-34-3 tert-butyl 4-(N-methyl-4-(4-methoxyphenyl)-1H-imidazole-1-carboxamido)piperidine-1-carboxylate 
• 1233855-25-8 N-cyclohexyl-4-(4-methoxyphenyl)-N-methyl-1H-imidazole-1-carboxamide 
• 190377-29-8 1-methyl-5-(4-methoxyphenyl)-1H-imidazole 
• 1415003-58-5 methyl 7-(4-(4-methoxyphenyl)-1H-imidazol-1-yl)-5-methyl-2,3-dihydrobenzo[b]oxepine-4-carboxylate 
• 702688-85-5 4-(4-Methoxyphenyl)-N,N-dimethyl-1H-imidazole-1-sulfonamide 

Relevant articles and documents

Efficient total synthesis of lissodendrin b, 2-aminoimidazole marine alkaloids isolated from lissodendoryx (acanthodoryx) fibrosa

Lissodendrin B is a 2-aminoimidazole alkaloid bearing a (p-hydroxyphenyl) glyoxal moiety that was isolated from the Indonesian sponge Lissodendoryx (Acanthodoryx) fibrosa. We reported the first efficient total synthesis of Lissodendrin B. The precursor 4,5-disubstituted imidazole was obtained through Suzuki coupling and Sonogashira coupling reactions from 4-iodoimidazole. C2-azidation and reduction of the azide then provided the core structures of Lissodendrin B. Subsequent triple-bond oxidation, demethylation, and deacetylation gave the final product. The synthesis approach consists of ten steps with an overall yield of 1.1% under mild reaction conditions, and it can be applied for future analog synthesis and biological studies.

Preparation of Imidazole Derivatives via Bisfunctionalization of Alkynes Catalyzed by Ruthenium Carbonyl

A one-step, oxidative bisfunctionalization of alkynes to generate cis -enediol diacetates catalyzed by ruthenium carbonyl (triruthenium dodecacarbonyl) is presented. The reaction was performed using the alkyne, (diacetoxyiodo)benzene, Ru 3 (CO) 12 as the catalyst, and toluene as the solvent at 100 °C to give the cis -enediol diacetates in up to 82percent yields. This method overcomes the shortcomings of existing methods, such as tedious reaction steps, substrate limitations, and the use of toxic reagents. Furthermore, the reaction of module cis -enediol diacetates with ammonium carbonate [(NH 4) 2 CO 3 ] in an alcohol solvent gave imidazole derivatives in 37-84percent yields, thus providing a simple and mild new method for the synthesis of imidazole compounds.

Imidazole analogues of resveratrol: Synthesis and cancer cell growth evaluation

Novel trans-restricted analogues of resveratrol in which the C-C double bond of the natural derivative has been replaced by diaryl substituted imidazole analogues have been designed. The syntheses of 1,4-, 2,4-, and 2,5-diarylimidazoles, in which the two