35520-41-3Relevant articles and documents
Formation of Enamines via Catalytic Dehydrogenation by Pincer-Iridium Complexes
Lu, Yansong J.,Zhang, Xiawei,Malakar, Santanu,Krogh-Jespersen, Karsten,Hasanayn, Faraj,Goldman, Alan S.
supporting information, p. 3020 - 3028 (2020/03/23)
Di-isopropylphosphino-substituted pincer-ligated iridium catalysts are found to be significantly more effective for the dehydrogenation of simple tertiary amines to give enamines than the previously reported di-t-butylphosphino-substituted species. It is
SUBSTITUTED BICYCLIC COMPOUNDS AS mPGES-1 INHIBITORS
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Page/Page column 39; 40, (2014/10/29)
The present disclosure is directed to compounds of formula (I), and pharmaceutically acceptable salts thereof, as mPGES-1 inhibitors. These compounds are inhibitors of the microsomal prostaglandin E synthase-1 (mPGES-1) enzyme and are therefore useful in the treatment of pain and/or inflammation from a variety of diseases or conditions, such as asthma, osteoarthritis, rheumatoid arthritis, acute or chronic pain and neurodegenerative diseases.
2-(arylimino-methyl)-3-dialkylaminoacrylonitriles, a process for their preparation and their use
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, (2008/06/13)
2-(Arylimino-methyl)-3-dialkylaminoacrylonitriles can be obtained by reaction of β-anilino-acrylonitriles with ortho-formamides. They are suitable as starting substances for the preparation of 4-amino-5-iminiummethylene-2-pyrimidines or 4-amino-5-formyl-2