355381-86-1

Basic information

• Product Name: (2,3-dimethoxy-benzyl)-(2-nitro-benzyl)-amine
• Synonyms: (2,3-dimethoxy-benzyl)-(2-nitro-benzyl)-amine
• CAS NO: 355381-86-1
• Molecular Weight: 302.33
• Mol File: 355381-86-1.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: (2,3-dimethoxy-benzyl)-(2-nitro-benzyl)-amine(CAS DataBase Reference)
• NIST Chemistry Reference: (2,3-dimethoxy-benzyl)-(2-nitro-benzyl)-amine(355381-86-1)
• EPA Substance Registry System: (2,3-dimethoxy-benzyl)-(2-nitro-benzyl)-amine(355381-86-1)

Safety Data

• Hazardous Substances Data: 355381-86-1(Hazardous Substances Data)

Upstream product

• 4393-09-3 2,3-dimethoxybenzyl amine 
• 552-89-6 2-nitro-benzaldehyde 

Downstream Products

• 3717-25-7 2-nitrobenzaldehyde oxime 
• 868775-48-8 C-(2-nitrophenyl)-N-(2,3-dimethoxybenzyl)-nitrone 

Relevant articles and documents

One-pot synthesis and hydroxylaminolysis of asymmetrical acyclic nitrones

Aromatic aldehydes 1 were reductively aminated to the corresponding secondary amines 2 using NaBH4 in methanol in good yields. Amines 2 were oxidized with H2O2-WO42- regioselectively to nitrones 3, the structures of which were easily determined by reacting them with hydroxylamine hydrochloride as well as by spectral means. The products of hydroxylaminolysis in ether proved to be the corresponding benzaldehyde oximes 4 and benzyl or methyl hydroxylamine hydrochlorides 5. Copyright Taylor & Francis, Inc.