35599-77-0

Basic information

• Product Name: TRIDECANE,1-IODO-
• Synonyms: TRIDECANE,1-IODO-;1-Iodotridecane;Tridecyl iodide
• CAS NO: 35599-77-0
• Molecular Formula: C₁₃H₂₇I
• Molecular Weight: 310.26
• Mol File: 35599-77-0.mol
• Article Data: 7

Chemical Properties

• Melting Point: 12.3°C
• Boiling Point: 295.12°C (estimate)
• Appearance: /
• Density: 1.1708 (rough estimate)
• Refractive Index: 1.4812
• CAS DataBase Reference: TRIDECANE,1-IODO-(CAS DataBase Reference)
• NIST Chemistry Reference: TRIDECANE,1-IODO-(35599-77-0)
• EPA Substance Registry System: TRIDECANE,1-IODO-(35599-77-0)

Safety Data

• Hazardous Substances Data: 35599-77-0(Hazardous Substances Data)

Usage

Uses

1-Iodotridecane is a useful building block for complex organic molecules. It also have been shown exhibiting antimicrobial activities against bacterial and Candida infections.

Upstream product

• 112-70-9 tridecan-1-ol 
• 1436673-44-7 C₁₈H₃₆O₂ 
• 108604-32-6 2-(tridec-2-yn-1-yloxy)tetrahydro-2H-pyran 
• 28267-29-0 ethyl tridecanoate 
• 765-09-3 1-bromotridecane 

Downstream Products

• 124210-60-2 1-(3,5-dimethoxy-phenyl)-pentadecan-1-one 
• 630-01-3 n-hexacosane 
• 65193-89-7 dodecyl-methyl ether 
• 123394-82-1 (R)-1-tridecyloxy-2,3-dibenzyloxypropane 
• 115198-05-5 Pentadec-1-ynyl-benzene 
• 16742-51-1 methyl (R)-2-hydroxyhexadecanoate 
• 105563-10-8 (2s,3R)-2-<(benzyloxycarbonyl)amino>-1,3-dihydroxy-4-octadecyne 
• 105617-35-4 N-CBZ-cis-sphingosine 
• 3542-12-9 (2S,3R,E)-2-aminooctadec-4-ene-1,3-diol 
• 105563-12-0 N-CBZ-dihydrosphingosine 

Relevant articles and documents

First total synthesis of paracaseolide A

The first total synthesis of the paracaseolide A, a very unusual tetraquinane oxa-cage bislactone recently isolated from the mangrove Sonneratia paracaseolaris, has been achieved. The final step and culmination of the eight-step synthetic sequence is a [4 + 2] dimerization of a 4-hydroxybutenolide, generated by singlet oxygen-mediated oxidation of a furan precursor.

METHODS FOR THE SYNTHESIS OF PLASMALOGENS AND PLASMALOGEN DERIVATIVES, AND THERAPEUTIC USES THEREOF

A method for preparing plasmalogens and derivatives thereof represented by Formula B, wherein R1 and R2 are similar or different, derived from fatty acids; R3 is selected from hydrogen and small alkyl groups. The synthetic route involves production of novel cyclic plasmalogen precursors of Formula A and their conversion to plasmalogens and plasmalogen derivatives of Formula B. Also disclosed is the therapeutic use of plasmalogens and derivatives thereof as produced by the synthetic route of the present invention.

A dialkynoyl analogue of DOPE improves gene transfer of lower-charged, cationic lipoplexes

Positively-charged gene delivery agents, such as cationic liposomes, typically prepared by mixing a cationic lipid and a neutral lipid in a 1: 1 molar ratio, exhibit a fundamental flaw: on the one hand, the charge encourages cell uptake; on the other hand, the charge leads to aggregation in vivo with anionic serum components. We herein report a more phase-stable analogue of the zwitterionic and fusogenic lipid DOPE that allows for the reduction of the cationic lipid component of the liposome from 50 to 9 mol% with almost no apparent loss in transfection activity. This reduction in charge may induce important in vivo stability whilst still imparting high cell uptake and transgene expression. The Royal Society of Chemistry 2006.