35601-91-3Relevant articles and documents
Differential functional theory and molecular docking studies of newly synthesized carbamates
Danish, Muhammad,Raza, Muhammad A.,Anwar, Uzma,Rashid, Umer,Ahmed, Zaheer
, p. 1408 - 1415 (2019/05/15)
Four new carbamates (RZ1–RZ4) were synthesized from different amine moieties through reported methods. The reaction was monitored using thin layer chromatography and characterization was done using m.p., fourier-transform infrared spectroscopy (FTIR), and X-ray diffraction (XRD) techniques. Density functional theory (DFT) studies were carried out using Gaussian 09 software to compare the theoretical and practical parameters of the synthesized compounds. Highest occupied molecular orbital (HOMO) and lowest unoccupied molecular orbital (LUMO) were also drawn to calculate the energy difference between orbitals. In-vitro enzyme inhibition potential against acetylcholine esterase (AChE), butyrylcholine esterase (BChE), and protease was checked through standard protocols that suggested moderate inhibition against selected enzymes. Docking studies were also carried out, which depicted that these compounds have ability to bind on the active site of AChE and BChE.
1,7-palladium migration via C-H activation, followed by intramolecular amination: Regioselective synthesis of benzotriazoles
Zhou, Jun,He, Jianjun,Wang, Binjie,Yang, Weijun,Ren, Hongjun
supporting information; experimental part, p. 6868 - 6870 (2011/06/21)
A novel 1,7-palladiummigration-cyclization-dealkylation sequence for the regioselective synthesis of benzotriazoles has been developed. These reactions proceed in excellent yields with high regioselectivities. The mechanism of the reaction has also been investigated.
Unexpected Reaction of Oximinoacetoacetate with Amines: A Novel Synthesis of Carbamates
Elghamry, Ibrahim
experimental part, p. 3010 - 3015 (2009/12/01)
The synthesis of alkyl carbamates by a solvent-free reaction of oximinoacetoacetate and amine at 130C is reported. A preliminary mechanism to this unexpected reaction is also given.