356086-86-7

Basic information

• Product Name: 4-P-TOLYLAMINO-BUTAN-1-OL
• Synonyms: AKOS BBB/428;4-P-TOLYLAMINO-BUTAN-1-OL;TIMTEC-BB SBB000209
• CAS NO: 356086-86-7
• Molecular Formula: C11H17NO
• Molecular Weight: 179.26
• Mol File: 356086-86-7.mol
• Article Data: 7

Chemical Properties

• Boiling Point: 329.9 °C at 760 mmHg
• Flash Point: 133.3 °C
• Appearance: /
• Density: 1.041 g/cm³
• Vapor Pressure: 6.9E-05mmHg at 25°C
• Refractive Index: 1.565
• CAS DataBase Reference: 4-P-TOLYLAMINO-BUTAN-1-OL(CAS DataBase Reference)
• NIST Chemistry Reference: 4-P-TOLYLAMINO-BUTAN-1-OL(356086-86-7)
• EPA Substance Registry System: 4-P-TOLYLAMINO-BUTAN-1-OL(356086-86-7)

Safety Data

• Hazard Codes: Xi
• HazardClass: IRRITANT
• Hazardous Substances Data: 356086-86-7(Hazardous Substances Data)

Usage

General Description

4-P-TOLYLAMINO-BUTAN-1-OL, also known as p-toluidine butanol, is an organic compound with the chemical formula C11H17NO. It is a white to off-white crystalline solid that is insoluble in water but soluble in organic solvents. This chemical is commonly used as an intermediate in the manufacturing of pharmaceuticals, dyes, and other organic compounds. It has a variety of industrial applications, including as a reagent in organic synthesis and as a component in the production of chemical products. While it has no known major health hazards, it is important to handle this compound with care and in accordance with safety guidelines.

InChI:InChI=1/C11H17NO/c1-10-4-6-11(7-5-10)12-8-2-3-9-13/h4-7,12-13H,2-3,8-9H2,1H3

Upstream product

• 412283-85-3 2-p-tolyl-3,6-dihydro-2H-[1,2]oxazine 
• 13325-10-5 4-Aminobutanol 
• 624-31-7 4-tolyl iodide 
• 109-99-9 tetrahydrofuran 
• 99-99-0 1-methyl-4-nitrobenzene 
• 106-49-0 p-toluidine 
• 6117-80-2 1,4-butenediol 

Relevant articles and documents

A new palladium-mediated approach to 4-N-arylamino-1-butanols from peroxidic tetrahydrofuran and primary aromatic amines

Reaction of primary aromatic amines with peroxidic tetrahydrofuran (THF) in the presence of hydrogen and 10% palladium on carbon catalyst results in THF ring opening to give 4-N-arylamino-1-butanols in a good yield. The reaction mechanism is believed to i

An efficient and atom-economical route to: N -aryl amino alcohols from primary amines

In this paper we reported a novel method for generation of N-aryl amino alcohols from N,N-disubstituted picolinamides through reduction/ring-opening reaction with NaBH4. The N,N-disubstituted picolinamides can be easily obtained from primary am

Rhodium(III)-catalyzed N-nitroso-directed C-H addition to ethyl 2-oxoacetate for cycloaddition/fragmentation synthesis of indazoles

RhIII-catalyzed N-nitroso-directed C-H addition to ethyl 2-oxoacetate allows subsequent construction of indazoles, a privileged heterocycle scaffold in synthetic chemistry, through the exploitation of reactivity between the directing group and installed group. The formal [2+2] cycloaddition/fragmentation reaction pathway identified herein, a unique reactivity pattern hitherto elusive for the N-nitroso group, emphasizes the importance of forward reactivity analysis in the development of useful C-H functionalization-based synthetic tools. The synthetic utility of the protocol is demonstrated with the synthesis of a tri-cyclic-fused ring system. The diversity of covalent linkages available for the nitroso group should enable the extension of the genre of reactivity reported herein to the synthesis of other types of heterocycles.