35616-03-6

Basic information

• Product Name: 1,4-Benzenediol, mono(4-methylbenzenesulfonate)
• Synonyms: 4-hydroxyphenyl tosylate;4-(Toluol-4-sulfonyloxy)-phenol;4-(toluene-4-sulfonyloxy)-phenol;4-tosyloxyphenol;4-(tosyloxy)phenol;4-(4'-methylbenzenesulfonyloxy)phenol
• CAS NO: 35616-03-6
• Molecular Formula: C13H12O4S
• Molecular Weight: 264.302
• Mol File: 35616-03-6.mol
• Article Data: 10

Chemical Properties

• CAS DataBase Reference: 1,4-Benzenediol, mono(4-methylbenzenesulfonate)(CAS DataBase Reference)
• NIST Chemistry Reference: 1,4-Benzenediol, mono(4-methylbenzenesulfonate)(35616-03-6)
• EPA Substance Registry System: 1,4-Benzenediol, mono(4-methylbenzenesulfonate)(35616-03-6)

Safety Data

• Hazardous Substances Data: 35616-03-6(Hazardous Substances Data)

Upstream product

• 109501-52-2 1-(α-hydroperoxy-isopropyl)-4-(toluene-4-sulfonyloxy)-benzene 
• 82969-01-5 4-acetoxyphenyl tosylate 
• 207500-64-9 4-(benzyloxy)phenyl 4-methylbenzenesulfonate 
• 98-59-9 p-toluenesulfonyl chloride 
• 123-31-9 hydroquinone 
• 67-56-1 methanol 
• 2581-43-3 cyclohexane-1,4-diyl bis(4-methylbenzenesulfonate) 
• 157259-26-2 4-(allyloxy)phenyl-4-methylbenzenesulfonate 
• 92346-02-6 cyclohexanone O-<4-(tosyloxy)phenyl>oxime 
• 1233362-19-0 C₁₉H₁₅NO₈S₂ 
• 107-18-6 allyl alcohol 

Downstream Products

• 89232-65-5 4-(tosyloxy)phenoxyamine 
• 207500-64-9 4-(benzyloxy)phenyl 4-methylbenzenesulfonate 
• 80459-48-9 4-tosyloxybenzaldehyde 
• 92-88-6 4,4'-Dihydroxybiphenyl 
• 1098336-64-1 toluene-4-sulfonic acid 4-trifluoromethoxy-phenyl ester 
• 59722-66-6 O-Ethyl S-n-propyl O-[4-(p-toluenesulfonyloxy)phenyl] phosphorothiolate 
• 3899-91-0 4-methoxyphenyl p-toluenesulfonate 
• 123-31-9 hydroquinone 

Relevant articles and documents

Selective deprotection of phenolic polysulfonates

Nosylates of phenols can be selectively deprotected by thiocresol anions in DMSO. Successful deprotection can be accomplished in molecules containing aryl-appended halides, ethers, aldehydes, alkanesulfonates or arylsulfonates. Nosylate deprotection is accomplished by the CS bond rupture which is believed to proceed by nucleophilic aromatic substitution.

Ether aryl sulfonic acid esters with improved antimalarial/anticancer activities

Our previous report showed that our current benchmark agent, 4-methoxyphenyl p-toluenesulibnate, is a selective antimalarial/anticancer agent. A series of related sulfones and sulfonic acid esters is now examined. 4-Allyloxyphenyl p-toluenesulfonate is a superior antimalarial/anticancer agent. 4-Methoxyphenyl 4-nitrobenzenesulfonate is a superior antimalarial agent, but shows poorer inhibition of human skin cancer cells. CSIRO 2006.

Development of a catalytic electron transfer system mediated by transition metal ate complexes: Applicability and tunability of electron-releasing potential for organic transformations

We have developed a catalytic electron transfer (ET) system composed of a transition metal ate complex (Me3M(II)Li; M = Co(II), Mn(II), Fe(II)) and magnesium. This system (catalytic Me3M(II)Li/Mg) turned out to be effective for various ET reactions, such as the desulfonylation of N-phenylsulfonyl amides, and others (the chemoselective cleavage of O-allyl groups, the reduction of nitro groups, the partial reduction of diketones, and the reductive coupling of diphenyliodonium salt). The ET ability of this system can be tuned by changing the ligands of the ate complexes. This tunability was experimentally and electrochemically demonstrated: alkoxy-ligated and dianion-type ET ate complexes showed attenuated and enhanced reducing abilities, respectively. The modification of the ET abilities was evaluated by means of electrochemical measurements and chemical reactions. These results provide a basis for the design of various tailor-made ET ate complexes.