356560-89-9

Basic information

• Product Name: 1-(benzo[d][1,3]dioxol-5-yl)-2-(6-Methylpyridin-2-yl)ethanone
• Synonyms: 1-(benzo[d][1,3]dioxol-5-yl)-2-(6-Methylpyridin-2-yl)ethanone;1-(1,3-benzodioxol-5-yl)-2-(6-methyl-2-pyridinyl)ethanone
• CAS NO: 356560-89-9
• Molecular Formula: C₁₅H₁₃NO₃
• Molecular Weight: 255.26862
• Mol File: 356560-89-9.mol
• Article Data: 6

Chemical Properties

• Appearance: /
• CAS DataBase Reference: 1-(benzo[d][1,3]dioxol-5-yl)-2-(6-Methylpyridin-2-yl)ethanone(CAS DataBase Reference)
• NIST Chemistry Reference: 1-(benzo[d][1,3]dioxol-5-yl)-2-(6-Methylpyridin-2-yl)ethanone(356560-89-9)
• EPA Substance Registry System: 1-(benzo[d][1,3]dioxol-5-yl)-2-(6-Methylpyridin-2-yl)ethanone(356560-89-9)

Safety Data

• Hazardous Substances Data: 356560-89-9(Hazardous Substances Data)

Usage

Type of Compound

Ketone

Structure

Contains a benzo[d][1,3]dioxole ring fused to a pyridine ring

Pharmaceutical Research

Used in the study of potential biological activities

Drug Discovery

Investigated for its potential as an anti-cancer agent and treatment for Alzheimer's disease

Medicinal Chemistry

Utilized as a building block for the synthesis of various organic compounds

Unique Features

a. Valuable compound for further research and development
b. Potential biological activities make it an interesting subject for study
c. Unique structure contributes to its potential applications in the pharmaceutical industry

Upstream product

• 108-48-5 2,6-dimethylpyridine 
• 6951-08-2 ethyl 1,3-benzodioxole-5-carboxylate 
• 147030-72-6 benzo[1,3]dioxole-5-carboxylic acid methoxymethylamide 
• 326-56-7 methyl 3,4-methylenedioxybenzoate 

Downstream Products

• 356560-76-4 1-(benzo[1,3]dioxol-5-yl)-2-(6-methylpyridin-2-yl)ethane-1,2-dione 
• 752260-31-4 1-(benzo[1,3]dioxol-5-yl)-2-bromo-2-(6-methylpyridin-2-yl)ethanone 
• 710946-97-7 4-[4-benzo[1,3]dioxol-5-yl-5-(6-methyl-pyridin-2-yl)-[1,2,3]triazol-2-ylmethyl]-benzonitrile 
• 710947-09-4 4-[4-benzo[1,3]dioxol-5-yl-5-(6-methyl-pyridin-2-yl)-[1,2,3]triazol-2-yl]-benzonitrile 

Relevant articles and documents

Synthesis and biological evaluation of 5-(pyridin-2-yl)thiazoles as transforming growth factor-β type1 receptor kinase inhibitors

A series of 5-(pyridin-2-yl)thiazoles (14a-l and 15a-l) has been synthesized and evaluated for their ALK5 inhibitory activity in cell-based luciferase reporter assays. Among them, 3-[[5-(6-methylpyridin-2-yl)-4-(quinoxalin-6-yl)thiazol-2-ylamino]methyl ]b

Tri-substituted heteroaryls and methods of making and using the same

Compounds of formula (I) possess unexpectedly high affinity for Alk 5 and/or Alk 4, and can be useful as antagonists thereof for preventing and/or treating numerous diseases, including fibrotic disorders. In one embodiment, the invention features a compound of the general formula (I).

Novel fused heteroaromatic compounds as transforming growth factor (TGF) inhibitors

Novel fused heteroaromatic compounds, including derivatives thereof, to intermediates for their preparation, to pharmaceutical compositions containing them and to their medicinal use are described. The compounds of the present invention are potent inhibitors of transforming growth factor (“TGF”)-β signaling pathway. They are useful in the treatment of various TGF-related disease states including, for example, cancer and fibrotic diseases.