35657-08-0Relevant articles and documents
Design, synthesis, and anti-Helicobacter pylori activity of erythromycin A (E)-9-oxime ether derivatives
Nam, Ghilsoo,Kang, Tae Won,Shin, Jung Hyu,Choi, Kyung Il
, p. 569 - 572 (2007/10/03)
The synthesis and anti-Helicobacter pylori (H. pylori) activity evaluation of a new series of erythromycin A (E)-9-oxime ether derivatives are described. These compounds exhibited comparable in vitro anti-H. pylori activity and improved acid stability com
p-Anisyloxymethyl Group, a Novel Oxidatively Removable Acetal Type OH-Protecting Group
Masaki, Yukio,Iwata, Ikuhiro,Mukai, Isao,Oda, Hirohisa,Nagashima, Hiromu
, p. 659 - 662 (2007/10/02)
Protection of various types of alcohols with p-anisyloxymethyl (p-AOM) chloride gave the corresponding p-AOM ethers which were deprotected with ceric ammonium nitrate efficiently.Chemoselective removal either of p-AOM group or of tetrahydropyranyl group is also reported.
5-Fluorouracil derivatives
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, (2008/06/13)
5-Fluorouracil derivatives and a process for their preparation are provided. The 5-fluorouracil derivatives according to the invention have the general formula: STR1 R1 and R2 are the same or different and are hydrogen or STR2 with the proviso that both R1 and R2 are not hydrogen at the same time. A1, A2 and A3 are independently selected from hydrogen, and optionally substituted alkoxy and phenyloxy; at least one of A1, A2 and A3 being other than hydrogen. The 5-fluorouracil derivative is prepared by condensing 5-fluorouracil with a halide of the formula: STR3 in the presence of a base. The 5-fluorouracils according to the invention show anti-tumor activity.