35665-58-8

Basic information

• Product Name: 9-(2-deoxypentofuranosyl)-N,N-dimethyl-9H-purin-6-amine
• CAS NO: 35665-58-8
• Molecular Formula: C₁₂H₁₇N₅O₃
• Molecular Weight: 279.2951
• Mol File: 35665-58-8.mol
• Article Data: 8

Chemical Properties

• Boiling Point: 565.4°C at 760 mmHg
• Flash Point: 295.8°C
• Density: 1.59g/cm³
• Vapor Pressure: 1.27E-13mmHg at 25°C
• Refractive Index: 1.73
• CAS DataBase Reference: 9-(2-deoxypentofuranosyl)-N,N-dimethyl-9H-purin-6-amine(CAS DataBase Reference)
• NIST Chemistry Reference: 9-(2-deoxypentofuranosyl)-N,N-dimethyl-9H-purin-6-amine(35665-58-8)
• EPA Substance Registry System: 9-(2-deoxypentofuranosyl)-N,N-dimethyl-9H-purin-6-amine(35665-58-8)

Safety Data

• Hazardous Substances Data: 35665-58-8(Hazardous Substances Data)

Upstream product

• 124-40-3 dimethyl amine 
• 158782-63-9 9-(3,5-di-O-acetyl-2-deoxy-β-D-erythro-pentofuranosyl)-6-(1,2,4-triazol-4-yl)purine 
• 163632-55-1 9-(2-deoxy-β-D-erythro-pentofuranosyl)-6-(1,2,4-triazol-4-yl)purine 
• 87-42-3 6-chloropurine 
• 3601-89-6 Hoffer's chlorosugar 
• 958-09-8 2'-deoxy-D-adenosine 
• 17318-24-0 3',5'-di-O-acetyl-2'-deoxyadenosine 
• 156517-72-5 6-chloro-9-(3,5-bis-O-acetyl-2-deoxy-β-D-erythro-pentofuranosyl)purine 
• 951-78-0 2'-deoxyuridine 
• 938-55-6 6-Dimethylaminopurine 
• 74-88-4 methyl iodide 
• 74230-06-1 trimethylselenonium hydroxyde 
• 17287-03-5 trimethylsulphonium hydroxide 
• 91713-46-1 6-Chloro-9-(2-deoxy-3,5-di-O-p-toluoyl-β-D-erythro-pentofuranosyl)purine 

Downstream Products

• 938-55-6 6-Dimethylaminopurine 

Relevant articles and documents

5′-O-Masked 2′-deoxyadenosine analogues as lead compounds for hepatitis C virus (HCV) therapeutic agents

On the basis of our previous study on antiviral agents against the severe acute respiratory syndrome (SARS) coronavirus, a series of nucleoside analogues whose 5′-hydroxyl groups are masked by various protective groups such as carboxylate, sulfonate, and

Efficient conversion of 6-aminopurines and nucleosides into 6-substituted analogues via novel 6-(1,2,4-triazol-4-yl)purine derivatives

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ACIDIC HYDROLYSIS OF 6-SUBSTITUTED 9-(2-DEOXY-β-D-ERYTHRO-PENTOFURANOSYL)PURINES AND THEIR 9-(1-ALKOXYETHYL) COUNTERPARTS: KINETICS AND MECHANISM.

The rate constants for the hydrolysis of several 6-substituted 9-(2-deoxy-β-D-erythro-pentofuranosyl)purines and 9-(1-alkoxyethyl)purines have been measured at different concentrations of oxonium ion.The effects that varying the polar nature of the alkoxy group exerts on the hydrolysis of unsubstituted 9-(1-alkoxyethyl)purines are interpreted to indicate that the reaction proceeds by a rate-limiting departure of the protonated base moiety with a concomitant formation of an alkoxyethyl oxocarbenium ion.The same mechanism is applied to the hydrolysis of 9-(2-deoxy-β-D-erythro-pentofuranosyl)purines by comparing the influences that 6-substituents have on the reactivity of these compounds and their 9-(1-alkoxyethyl) counterparts.No sign of anomerisation was detected, when the hydrolysis of 2'-deoxyadenosine was followed by 1H NMR spectroscopy.