356783-27-2 Usage
Description
Methyl 6-fluoro-3-oxo-3,4-dihydro-2-pyrazinecarboxylate is an organic compound that serves as a key building block in the synthesis of Favipiravir (F103350), an antiviral medication. methyl 6-fluoro-3-oxo-3,4-dihydro-2-pyrazinecarboxylate is characterized by its fluorinated pyrazine core, which contributes to its biological activity and potential applications in the pharmaceutical industry.
Uses
Used in Antiviral Applications:
Methyl 6-fluoro-3-oxo-3,4-dihydro-2-pyrazinecarboxylate is used as a building block for the synthesis of Favipiravir, an antiviral drug. Favipiravir has demonstrated efficacy in the treatment of advanced Ebola virus infection in small animal models. It effectively suppresses the replication of Zaire Ebola virus, preventing lethal outcomes in 100% of the animals studied. As a result, Favipiravir is considered a promising candidate for the treatment of Ebola hemorrhagic fever.
Used in Pharmaceutical Industry:
In the pharmaceutical industry, methyl 6-fluoro-3-oxo-3,4-dihydro-2-pyrazinecarboxylate is used as an essential intermediate in the development of new antiviral drugs. Its unique chemical structure and properties make it a valuable component in the design and synthesis of novel therapeutic agents targeting various viral infections.
Check Digit Verification of cas no
The CAS Registry Mumber 356783-27-2 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 3,5,6,7,8 and 3 respectively; the second part has 2 digits, 2 and 7 respectively.
Calculate Digit Verification of CAS Registry Number 356783-27:
(8*3)+(7*5)+(6*6)+(5*7)+(4*8)+(3*3)+(2*2)+(1*7)=182
182 % 10 = 2
So 356783-27-2 is a valid CAS Registry Number.
356783-27-2Relevant articles and documents
Novel pyrazine derivatives or salts thereof, pharmaceutical composition containing the same, and production intermediates thereof
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, (2008/06/13)
Pyrazine derivatives represented by general formula [1]: 1wherein the variables are as defined in the specification, or salts thereof have an excellent antiviral activity and are useful as a therapeutic agent for treating viral infections. Further, fluoropyrazine-carboxamide derivatives represented by general formula [2]: 2wherein the variables are as defined in the specification, or salts thereof are useful as an intermediate for production of the compounds of general formula [1], and as an intermediate for production of the fluoropyrazine-carboxamide derivatives of which one typical example is 6-fluoro-3-hyroxy-2-pyrazine-carboxamide having an antiviral activity.