35711-47-8 Usage
Description
2,5-DIMETHYL-1-PYRIDIN-3-YL-1H-PYRROLE-3-CARBALDEHYDE is a heterocyclic aromatic compound with the molecular formula C15H14N2O. It features a pyrrole ring and a pyridine ring, along with a carbonyl group. This unique structure endows it with potential biological activities and makes it a valuable compound in organic synthesis and pharmaceutical research.
Uses
Used in Pharmaceutical Research:
2,5-DIMETHYL-1-PYRIDIN-3-YL-1H-PYRROLE-3-CARBALDEHYDE is used as a key intermediate in the synthesis of various pharmaceutical compounds for its potential therapeutic applications in treating diseases such as cancer and inflammatory disorders.
Used in Organic Synthesis:
In the field of organic synthesis, 2,5-DIMETHYL-1-PYRIDIN-3-YL-1H-PYRROLE-3-CARBALDEHYDE serves as a building block for creating more complex organic molecules, leveraging its reactive pyrrole and pyridine rings.
Used in Antioxidant Applications:
2,5-DIMETHYL-1-PYRIDIN-3-YL-1H-PYRROLE-3-CARBALDEHYDE is utilized as an antioxidant, providing protection against oxidative stress and damage in various chemical and biological systems.
Used in Antimicrobial Applications:
2,5-DIMETHYL-1-PYRIDIN-3-YL-1H-PYRROLE-3-CARBALDEHYDE is also used as an antimicrobial agent, exhibiting properties that help combat microbial growth, which can be beneficial in medical and industrial settings.
Check Digit Verification of cas no
The CAS Registry Mumber 35711-47-8 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 3,5,7,1 and 1 respectively; the second part has 2 digits, 4 and 7 respectively.
Calculate Digit Verification of CAS Registry Number 35711-47:
(7*3)+(6*5)+(5*7)+(4*1)+(3*1)+(2*4)+(1*7)=108
108 % 10 = 8
So 35711-47-8 is a valid CAS Registry Number.
InChI:InChI=1/C12H12N2O/c1-9-6-11(8-15)10(2)14(9)12-4-3-5-13-7-12/h3-8H,1-2H3
35711-47-8Relevant articles and documents
ANDROGEN RECEPTOR ANTAGONISTS
-
, (2019/08/26)
Compounds that inhibit the androgen receptor, pharmaceutical compositions comprising one or more of the compounds, as well as methods of treating cancer using such compounds are described.
Discovery and structure-activity relationships of pyrrolone antimalarials
Murugesan, Dinakaran,Mital, Alka,Kaiser, Marcel,Shackleford, David M.,Morizzi, Julia,Katneni, Kasiram,Campbell, Michael,Hudson, Alan,Charman, Susan A.,Yeates, Clive,Gilbert, Ian H.
, p. 2975 - 2990 (2013/05/23)
In the pursuit of new antimalarial leads, a phenotypic screening of various commercially sourced compound libraries was undertaken by the World Health Organisation Programme for Research and Training in Tropical Diseases (WHO-TDR). We report here the detailed characterization of one of the hits from this process, TDR32750 (8a), which showed potent activity against Plasmodium falciparum K1 (EC50 ～ 9 nM), good selectivity (>2000-fold) compared to a mammalian cell line (L6), and significant activity against a rodent model of malaria when administered intraperitoneally. Structure-activity relationship studies have indicated ways in which the molecule could be optimized. This compound represents an exciting start point for a drug discovery program for the development of a novel antimalarial.
