357183-11-0

Basic information

• Product Name: N,2-dimethoxy-N-methyl-4-nitrobenzamide
• Synonyms: N,2-dimethoxy-N-methyl-4-nitrobenzamide
• CAS NO: 357183-11-0
• Molecular Weight: 240.216
• Mol File: 357183-11-0.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: N,2-dimethoxy-N-methyl-4-nitrobenzamide(CAS DataBase Reference)
• NIST Chemistry Reference: N,2-dimethoxy-N-methyl-4-nitrobenzamide(357183-11-0)
• EPA Substance Registry System: N,2-dimethoxy-N-methyl-4-nitrobenzamide(357183-11-0)

Safety Data

• Hazardous Substances Data: 357183-11-0(Hazardous Substances Data)

Upstream product

• 2597-56-0 4-nitro-o-anisic acid 
• 619-19-2 2-hydroxy-4-nitrobenzoic acid 

Downstream Products

• 1319746-19-4 1-(2-methoxy-4-nitrophenyl)-5-methylhex-2-yn-1-one 
• 1319746-33-2 (Z)-4-((1-(4-amino-2-methoxyphenyl)-5-methyl-1-oxohex-2-en-3-yl)amino)-2-(benzyloxy)benzamide 
• 1319746-32-1 (Z)-4-((1-(4-amino-2-methoxyphenyl)-5-methyl-1-oxohex-2-en-3-yl)amino)-2-isopropoxybenzamide 
• 1319746-31-0 (Z)-4-((1-(4-amino-2-methoxyphenyl)-5-methyl-1-oxohex-2-en-3-yl)amino)-2-methoxybenzamide 
• 1319746-24-1 (Z)-2-(benzyloxy)-4-((1-(2-methoxy-4-nitrophenyl)-5-methyl-1-oxohex-2-en-3-yl)amino)benzamide 
• 1319746-23-0 (Z)-2-isopropoxy-4-((1-(2-methoxy-4-nitrophenyl)-5-methyl-1-oxohex-2-en-3-yl)amino)benzamide 
• 1319746-22-9 (Z)-2-methoxy-4-((1-(2-methoxy-4-nitrophenyl)-5-methyl-1-oxohex-2-en-3-yl)amino)benzamide 
• 357183-12-1 N,O-dimethyl 4-amino-2-methoxybenzohydroxamate 

Relevant articles and documents

Oligophenylenaminones as scaffolds for α-helix mimicry

The design and synthesis of small molecule α-helix mimetics has been a productive field over the past decade. These compounds have performed well in a variety of biological systems as functional disruptors of α-helix- mediated protein-protein interactions. In our studies we have continued to develop novel, more biologically compatible scaffolds, which are often easier to assemble and capable of mimicking longer and/or more diverse helices. To this end, we have constructed a new series of i, i+4, i+7 α-helix mimics based on the enaminone scaffold. These molecules represent a step forward in the pursuit of idealized monofacial α-helix mimetics.