3574-94-5

Basic information

• Product Name: 2-(1,3-thiazol-2-yl)-1H-benzimidazole
• Synonyms: 1H-benzimidazole, 2-(2-thiazolyl)-
• CAS NO: 3574-94-5
• Molecular Formula: C₁₀H₇N₃S
• Molecular Weight: 201.2477
• Mol File: 3574-94-5.mol
• Article Data: 3

Chemical Properties

• Boiling Point: 435.6°C at 760 mmHg
• Flash Point: 219.5°C
• Density: 1.406g/cm³
• Vapor Pressure: 8.63E-08mmHg at 25°C
• Refractive Index: 1.739
• CAS DataBase Reference: 2-(1,3-thiazol-2-yl)-1H-benzimidazole(CAS DataBase Reference)
• NIST Chemistry Reference: 2-(1,3-thiazol-2-yl)-1H-benzimidazole(3574-94-5)
• EPA Substance Registry System: 2-(1,3-thiazol-2-yl)-1H-benzimidazole(3574-94-5)

Safety Data

• Hazardous Substances Data: 3574-94-5(Hazardous Substances Data)

Usage

Class

Benzimidazole derivatives

Structural feature

Contains a thiazole ring

Biological activities

Antimicrobial, antiviral, and antitumor properties

Potential use in drug development

Yes

Application as a fluorescent probe

Detecting metal ions

Potential role in treatment

Cancer and infectious diseases

Upstream product

• 10200-59-6 Thiazole-2-carbaldehyde 
• 95-54-5 1,2-diamino-benzene 
• 10090-27-4 2-(4,5-dihydro-thiazol-2-yl)-1H-benzoimidazole 

Downstream Products

• 1207456-44-7 C₁₈H₁₂Cl₂N₄OS 
• 1207456-43-6 C₁₈H₁₃BrN₄OS 
• 1207456-42-5 C₁₈H₁₃ClN₄OS 
• 464895-50-9 Rh(H)2(PPh₃)2(2-(4-thiazolyl)benzimidazole)ClO₄ 

Relevant articles and documents

Microwave use of amidine compounds in the aqueous phase benzoate synthesis of benzimidazole compounds method

The invention discloses a microwave the use of amidine compounds in the aqueous phase benzoate synthesis of benzimidazole compounds, in the aqueous phase under microwave conditions adding benzoic amidine compound under alkaline condition [...] into benzimidazole reaction, invention an environment-friendly, the operation is simple, cheap and safe, efficient process for preparing benzimidazole method. Compared with the prior art, this method not only can be applied to a large number of functional groups, the productive rate is high, few by-products, and the operation is simple, safe, low cost, environmental protection; .

The structural basis of Cryptosporidium-specific IMP dehydrogenase inhibitor selectivity

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