35889-75-9

Basic information

• Product Name: 2-({2-[(4-methylbenzene)sulfonamido]benzene}amido)benzoic acid
• CAS NO: 35889-75-9
• Molecular Weight: 410.45
• Mol File: 35889-75-9.mol
• Article Data: 4

Chemical Properties

• CAS DataBase Reference: 2-({2-[(4-methylbenzene)sulfonamido]benzene}amido)benzoic acid(CAS DataBase Reference)
• NIST Chemistry Reference: 2-({2-[(4-methylbenzene)sulfonamido]benzene}amido)benzoic acid(35889-75-9)
• EPA Substance Registry System: 2-({2-[(4-methylbenzene)sulfonamido]benzene}amido)benzoic acid(35889-75-9)

Safety Data

• Hazardous Substances Data: 35889-75-9(Hazardous Substances Data)

Upstream product

• 610-14-0 2-nitrobenzyl chloride 
• 150256-42-1 2-({[(9H-fluoren-9-yl)methoxy]carbonyl}amino)benzoic acid 
• 326901-33-1 ethyl 2-(2-nitrobenzoylamino)-benzoate 
• 228581-79-1 ethyl 2-(2-aminobenzoylamino)-benzoate 
• 53705-10-5 ethyl 2-[2-(p-toluenesulfonylamino)benzoylamino]benzoate 
• 552-16-9 ortho-nitrobenzoic acid 
• 3808-20-6 4-methyl-N-[2-(4-oxo-4H-benzo[d][1,3]oxazin-2-yl)phenyl]benzenesulfonamide 
• 7664-93-9 sulfuric acid 
• 39031-30-6 5,11-bis-(toluene-4-sulfonyl)-5H,11H-dibenzo[b,f][1,5]diazocine-6,12-dione 

Relevant articles and documents

X-ray diffraction analysis and luminescence spectral study of crystal solvates of N-(N′-tosylanthranoyl)anthranilic acid with acetic acid and dimethylformamide

Two crystal modifications of N-(N′-tosylanthranoyl)anthranilic acid were studied by X-ray diffraction analysis and luminescence spectroscopy. One crystal modification is a crystal solvate with acetic acid and is characterized by green fluorescence. Another modification is a crystal solvate with DMF and exhibits blue fluorescence. The modifications differ in the melting point.

Synthesis, biological evaluation, and structure-activity relationships of 2-[2-(benzoylamino)benzoylamino]benzoic acid analogues as inhibitors of adenovirus replication

2-[2-Benzoylamino)benzoylamino]benzoic acid (1) was previously identified as a potent and nontoxic antiadenoviral compound (Antimicrob. Agents Chemother. 2010, 54, 3871). Here, the potency of 1 was improved over three generations of compounds. We found that the ortho, ortho substituent pattern and the presence of the carboxylic acid of 1 are favorable for this class of compounds and that the direction of the amide bonds (as in 1) is obligatory. Some variability in the N-terminal moiety was tolerated, but benzamides appear to be preferred. The substituents on the middle and C-terminal rings were varied, resulting in two potent inhibitors, 35g and 35j, with EC50 = 0.6 μM and low cell toxicity.