359-88-6 Usage
Description
METHYL 3-METHOXY-2-(TRIFLUOROMETHYL)PROPANOATE is an organic compound that is a byproduct of the synthesis of trifluoromethyl-substituted unsaturated acids. It is characterized by its unique chemical structure, which includes a trifluoromethyl group and a methoxy group attached to a propanoate backbone.
Uses
Used in Pharmaceutical Industry:
METHYL 3-METHOXY-2-(TRIFLUOROMETHYL)PROPANOATE is used as an intermediate in the synthesis of various pharmaceutical compounds for its unique reactivity and structural properties.
Used in Chemical Synthesis:
METHYL 3-METHOXY-2-(TRIFLUOROMETHYL)PROPANOATE is used as a building block in the synthesis of complex organic molecules, particularly those requiring a trifluoromethyl group for enhanced biological activity or stability.
Used in Agrochemical Industry:
METHYL 3-METHOXY-2-(TRIFLUOROMETHYL)PROPANOATE is used as a precursor in the development of new agrochemicals, such as pesticides and herbicides, due to its potential to improve the efficacy and selectivity of these compounds.
Used in Material Science:
METHYL 3-METHOXY-2-(TRIFLUOROMETHYL)PROPANOATE can be utilized in the development of novel materials with specific properties, such as improved thermal stability or chemical resistance, by incorporating the trifluoromethyl group into the material's structure.
Check Digit Verification of cas no
The CAS Registry Mumber 359-88-6 includes 6 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 3 digits, 3,5 and 9 respectively; the second part has 2 digits, 8 and 8 respectively.
Calculate Digit Verification of CAS Registry Number 359-88:
(5*3)+(4*5)+(3*9)+(2*8)+(1*8)=86
86 % 10 = 6
So 359-88-6 is a valid CAS Registry Number.
InChI:InChI=1/C6H9F3O3/c1-11-3-4(5(10)12-2)6(7,8)9/h4H,3H2,1-2H3
359-88-6Relevant articles and documents
Alkoxycarbonylation of 3,3,3-Trifluoropropyne: An Intriguing Reaction to Prepare Trifluoromethyl-Substituted Unsaturated Acid Derivatives
Scrivanti,Beghetto,Matteoli
, p. 543 - 547 (2007/10/03)
The addition of CO and methanol to 3,3,3-trifluoropropyne is catalysed by Pd(OAc)2 in the presence of (6-methylpyrid-2-yl)diphenylphosphine and CH3SO3H. The main products of the reaction are the methyl esters of 2-(trifluoromethyl)propenoic acid 1 and of 3-(trifluoromethyl)propenoic acid 2 (4,4,4-trifluorobut-2-enoic acid). The regioselectivity of the reaction can be controlled to a great extent by a suitable choice of the composition of the catalytic system and the reaction conditions. Thus, 1 can be obtained in 93% yield by using P(CO) = 20 atm and high ligand/Pd and acid/Pd ratios. On the other hand, selectivity up to 85% in 2 can be achieved using P(CO) = 80 atm and a low ligand/Pd ratio together with a high acid/Pd ratio. The reaction mechanism is also discussed.
