35944-64-0 Usage
Description
3-IODO-4-METHYLANILINE is an organic compound that serves as a crucial intermediate in the synthesis of various chemical and pharmaceutical products. It is characterized by its molecular structure, which includes an iodine atom at the 3rd position and a methyl group at the 4th position on the aniline backbone.
Uses
Used in Fine Chemicals Industry:
3-IODO-4-METHYLANILINE is used as a key intermediate in the production of fine chemicals. Its unique molecular structure allows for the creation of a wide range of specialty chemicals with specific properties and applications.
Used in Pharmaceutical Industry:
3-IODO-4-METHYLANILINE is utilized as a pharmaceutical intermediate, playing a vital role in the synthesis of various drugs. Its presence in the molecular structure can contribute to the drug's efficacy, safety, and overall performance.
Used in Synthesis of Specific Compounds:
3-IODO-4-METHYLANILINE is used as a starting material for the synthesis of specific compounds, such as 2-[((3-iodo-4-methyl)phenylimino)methyl]-5-nitrothiophene, which is derived from 5-nitro-2-thiophene-carboxaldehyde and 3-iodo-4-methylaniline. Additionally, it is used in the preparation of 1-(3-iodo-4-methylphenyl)-3-tert-butyl-2H-aminopyrazole (5), showcasing its versatility in chemical reactions and compound development.
Check Digit Verification of cas no
The CAS Registry Mumber 35944-64-0 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 3,5,9,4 and 4 respectively; the second part has 2 digits, 6 and 4 respectively.
Calculate Digit Verification of CAS Registry Number 35944-64:
(7*3)+(6*5)+(5*9)+(4*4)+(3*4)+(2*6)+(1*4)=140
140 % 10 = 0
So 35944-64-0 is a valid CAS Registry Number.
InChI:InChI=1/C7H8IN/c1-5-2-3-7(9)6(8)4-5/h2-4H,9H2,1H3
35944-64-0Relevant articles and documents
Complementary Site-Selective Halogenation of Nitrogen-Containing (Hetero)Aromatics with Superacids
Mamontov, Alexander,Martin-Mingot, Agnès,Métayer, Benoit,Karam, Omar,Zunino, Fabien,Bouazza, Fodil,Thibaudeau, Sébastien
supporting information, p. 10411 - 10416 (2020/07/30)
Site-selective functionalization of arenes that is complementary to classical aromatic substitution reactions remains a long-standing quest in organic synthesis. Exploiting the generation of halenium ion through oxidative process and the protonation of the nitrogen containing function in HF/SbF5, the chlorination and iodination of classically inert Csp2?H bonds of aromatic amines occurs. Furthermore, the superacid-promoted (poly)protonation of the molecules acts as a protection, favoring the late-stage selective halogenation of natural alkaloids and active pharmaceutical ingredients.
