3597-42-0

Basic information

• Product Name: 1-Naphthalenecarboxaldehyde,6-methoxy-(9CI)
• Synonyms: 1-Naphthalenecarboxaldehyde,6-methoxy-(9CI)
• CAS NO: 3597-42-0
• Molecular Formula: C₁₂H₁₀O₂
• Molecular Weight: 186.2066
• Product Categories: NAPHTALENE
• Mol File: 3597-42-0.mol
• Article Data: 7

Chemical Properties

• Appearance: /
• CAS DataBase Reference: 1-Naphthalenecarboxaldehyde,6-methoxy-(9CI)(CAS DataBase Reference)
• NIST Chemistry Reference: 1-Naphthalenecarboxaldehyde,6-methoxy-(9CI)(3597-42-0)
• EPA Substance Registry System: 1-Naphthalenecarboxaldehyde,6-methoxy-(9CI)(3597-42-0)

Safety Data

• Hazardous Substances Data: 3597-42-0(Hazardous Substances Data)

Upstream product

• 2437-17-4 6-hydroxy-1-naphthoic acid 
• 61109-48-6 6-methoxy-1-naphthalenecarboxylic acid methyl ester 
• 6500-64-7 5-(3'-methoxyphenyl)pentanoic acid 
• 36112-54-6 2-methoxy-6,7,8,9-tetrahydro-5H-benzocycloheptan-5-ol 
• 36112-55-7 2-methoxy-8,9-dihydro-7H-benzocycloheptene 
• 6500-65-8 2-methoxy-6,7,8,9-tetrahydro-benzocyclohepten-5-one 
• 83379-67-3 2-(2,4-dinitrophenyl)-7-methoxyisoquinolinium bromide 
• 82589-61-5 Ethyl 6-methoxy-1-naphthoate 
• 63469-49-8 1-iodo-6-methoxynaphthalene 
• 68-12-2 N,N-dimethyl-formamide 
• 77029-01-7 6-methoxy-[1]naphthonitrile 
• 61109-49-7 1-Hydroxymethyl-6-methoxynaphthalene 
• 36112-56-8 3-methoxy-5H-benzo[7]annulene 

Downstream Products

• 571206-45-6 6-hydroxy-1-naphthaldehyde 
• 83379-75-3 benzyl (6-methoxynaphthyl)carbamate 
• 82589-57-9 3-Methoxy-7,9,10,11,11a,12-hexahydrobenzopyrrolo<1,2-b>isoquinoline 
• 192384-22-8 4-Fluoro-2-[1-(6-methoxy-naphthalen-1-yl)-ethyl]-benzoic acid 
• 192384-04-6 4-fluoro-2-[1-(3-methoxynaphthoyl)]benzoic acid 
• 192384-21-7 1-[4-Fluoro-2-(6-methoxy-naphthalen-1-ylmethyl)-phenyl]-ethanone 
• 82590-38-3 (Z)-5-(6-Methoxy-naphthalen-1-yl)-4-nitro-pent-4-enoic acid ethyl ester 

Relevant articles and documents

Organocatalytic Atroposelective Arylation of 2-Naphthylamines as a Practical Approach to Axially Chiral Biaryl Amino Alcohols

The first phosphoric acid catalyzed direct arylation of 2-naphthylamines with iminoquinones for the atroposelective synthesis of axially chiral biaryl amino alcohols has been developed. This reaction constitutes a highly functional-group-tolerant route for the rapid construction of enantioenriched axially chiral biaryl amino alcohols, and is a rare example of 2-naphthylamines acting as nucleophiles in an organocatalytic enantioselective transformation. Furthermore, the products, which feature various halogen atoms, provide access to structurally diverse axially chiral amino alcohols through further transformations.

Fluorine-substituted derivatives of the carcinogenic dihydrodiol and diol epoxide metabolites of 7-methyl-, 12-methyl- and 7,12-dimethylbenz[a]anthracene

Stereospecific syntheses of the trans-3,4-dihydrodiol metabolites of 9- and 10-fluoro-7, 12-dimethylbenz[alanthracene, -7-methylbenz[a]anthracene, and -12-methylbenz[a]anthracene are described. These dihydrodiols are putative proximate carcinogenic metabolites that undergo activation by the P-450 microsomal enzymes to ultimate carcinogenic anti- and syn-diol epoxide metabolites that bind to nucleic acids in vivo. Syntheses of several of the anti- diol epoxide metabolites are also described.

Isoquinolinium Cycloadditions: Regiospecific Synthesis of 1-Naphthaldehydes and Conversion to 1-Naphthylamines

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