35981-63-6

Basic information

• Product Name: 2-(pyrrolidin-1-yl)pyridin-4-aMine
• Synonyms: 2-(pyrrolidin-1-yl)pyridin-4-aMine;2-(1-Pyrrolidinyl)-4-pyridinaMine
• CAS NO: 35981-63-6
• Molecular Formula: C9H13N3
• Molecular Weight: 163.21962
• Mol File: 35981-63-6.mol
• Article Data: 8

Chemical Properties

• Appearance: /
• CAS DataBase Reference: 2-(pyrrolidin-1-yl)pyridin-4-aMine(CAS DataBase Reference)
• NIST Chemistry Reference: 2-(pyrrolidin-1-yl)pyridin-4-aMine(35981-63-6)
• EPA Substance Registry System: 2-(pyrrolidin-1-yl)pyridin-4-aMine(35981-63-6)

Safety Data

• Hazardous Substances Data: 35981-63-6(Hazardous Substances Data)

Usage

General Description

2-(pyrrolidin-1-yl)pyridin-4-amine is a chemical compound with the molecular formula C9H12N2. It is a heterocyclic amine derivative containing a pyrrolidine ring and a pyridine ring. 2-(pyrrolidin-1-yl)pyridin-4-aMine has potential applications in the field of medicinal chemistry and drug development due to its ability to interact with biological targets such as receptors and enzymes. It may also be used as a building block in organic synthesis for the creation of more complex chemical structures. Additionally, its unique molecular structure makes it a valuable tool for understanding the structure-activity relationship of similar compounds in the pharmaceutical industry.

Upstream product

• 35981-61-4 4-nitro-2-pyrrolidin-1-ylpyridine-1-oxide 
• 123-75-1 pyrrolidine 
• 14432-12-3 4-Amino-2-chloropyridine 
• 914397-51-6 4-nitro-2-(pyrrolidin-1-yl)pyridine 

Relevant articles and documents

Selective Functionalization of Aminoheterocycles by a Pyrylium Salt

The functionalization of aminoheterocycles by using a pyrylium tetrafluoroborate reagent (Pyry-BF4) is presented. This reagent efficiently condenses with a great variety of heterocyclic amines and primes the C?N bond for nucleophilic aromatic substitution. More than 60 examples for the formation of C?O, C?N, C?S, or C?SO2R bonds are disclosed herein. In contrast to C?N activation through diazotization and polyalkylation, this method is characterized by its mild conditions and impressive functional-group tolerance. In addition to small-molecule derivatization, Pyry-BF4 allows the introduction of functional groups in a late-stage fashion to furnish highly functionalized structures.

QUINOLINES AND RELATED ANALOGS AS SIRTUIN MODULATORS

Provided herein are novel sirtuin-modulating compounds and methods of use thereof. The sirtuin-modulating compounds may be used for increasing the lifespan of a cell, and treating and/or preventing a wide variety of diseases and disorders including, for example, diseases or disorders related to aging or stress, diabetes, obesity, neurodegenerative diseases, cardiovascular disease, blood clotting disorders, inflammation, cancer, and/or flushing as well as diseases or disorders that would benefit from increased mitochondrial activity. Also provided are compositions comprising a sirtuin-modulating compound in combination with another therapeutic agent.

NOVEL AMINOMETHYL-PHENOL DERIVATIVES AS ANTIMALARIAL AGENTS

The invention relates to novel aminomethyl-phenol derivatives of formula I wherein R1 to R4, X, A and B are as defined for formula I and their use as active ingredients in the preparation of pharmaceutical compositions. The invention