359878-18-5 Usage
Piperidine derivative
A compound based on the piperidine ring structure A six-membered ring containing one nitrogen atom, with the structure of a saturated heterocyclic compound.
1-position methyl group
A methyl group (CH3) attached to the piperidine ring at the first position A substituent located on the first carbon atom of the piperidine ring.
4-position piperidin-4-amine
An amine group (NH2) attached to the piperidine ring at the fourth position A functional group containing a nitrogen atom with two hydrogen atoms bonded to it, located on the fourth carbon atom of the piperidine ring.
Benzyl group
A phenyl ring (a six-membered ring with alternating single and double carbon-carbon bonds) connected to a methylene group (CH2) A structural unit consisting of a phenyl ring connected to a single carbon atom.
Methyl substituent
A methyl group (CH3) attached to the benzyl group A substituent located on the benzyl ring, contributing to the structure's complexity.
Medicinal chemistry application
Used as a building block for the synthesis of various pharmaceuticals and bioactive compounds The compound serves as an essential component in creating a wide range of medications and biologically active substances.
Biological and pharmacological activities
Exhibits potential as an analgesic and a neuroprotective agent The compound has been shown to have possible therapeutic effects, including pain relief and protection of nerve cells.
Potential use in neurological disorders and mental health conditions
The compound has been studied for its possible applications in treating conditions related to the nervous system and mental health Its potential benefits in these areas are still being researched and explored.
Check Digit Verification of cas no
The CAS Registry Mumber 359878-18-5 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 3,5,9,8,7 and 8 respectively; the second part has 2 digits, 1 and 8 respectively.
Calculate Digit Verification of CAS Registry Number 359878-18:
(8*3)+(7*5)+(6*9)+(5*8)+(4*7)+(3*8)+(2*1)+(1*8)=215
215 % 10 = 5
So 359878-18-5 is a valid CAS Registry Number.
359878-18-5Relevant articles and documents
Synthesis and in vivo evaluation of [O-methyl-11C] 2-(4-methoxyphenyl)-N-methylbenzyl-N-(1-methylpiperidin-4-yl)acetamide as an imaging probe for 5-HT2A receptors
Prabhakaran, Jaya,Parsey, Ramin V.,Majo, Vattoly J.,Van Heertum, Ronald L.,Mann, J. John,Kumar, J.S. Dileep
, p. 1069 - 1077 (2006)
2-(4-Methoxyphenyl)-N-(4-methylbenzyl)-N-(1-methylpiperidin-4-yl)acetamide (AC90179, 4), a highly potent and selective competitive 5-HT2A antagonist, was labeled by [11C]-methylation of the corresponding desmethyl analogue 5 with [s
USE OF 4-AMINO-PIPERIDINES FOR TREATING SLEEP DISORDERS
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Page/Page column 104-105, (2010/11/28)
Inverse agonists and antagonists of serotonin receptors are disclosed for use in treating sleep disorders such as insomnia, and specifically sleep maintenance insomnia. The compound increase slow wave sleep, decrease the number of awakenings after sleep onset, and decrease the time awake after sleep onset.
