36050-35-8

Basic information

• Product Name: 2-Methyl-3-nitrothiophene-5-carboxylic Acid
• Synonyms: 2-Methyl-3-nitrothiophene-5-carboxylic Acid
• CAS NO: 36050-35-8
• Molecular Formula: C₆H₅NO₄S
• Molecular Weight: 187.1732
• Mol File: 36050-35-8.mol
• Article Data: 8

Chemical Properties

• Melting Point: 180-181 °C
• Boiling Point: 368.4°C at 760 mmHg
• Flash Point: 176.6°C
• Appearance: /
• Density: 1.565g/cm³
• Vapor Pressure: 4.45E-06mmHg at 25°C
• Refractive Index: 1.637
• Storage Temp.: 2-8°C
• PKA: 3.01±0.10(Predicted)
• CAS DataBase Reference: 2-Methyl-3-nitrothiophene-5-carboxylic Acid(CAS DataBase Reference)
• NIST Chemistry Reference: 2-Methyl-3-nitrothiophene-5-carboxylic Acid(36050-35-8)
• EPA Substance Registry System: 2-Methyl-3-nitrothiophene-5-carboxylic Acid(36050-35-8)

Safety Data

• Hazardous Substances Data: 36050-35-8(Hazardous Substances Data)

Usage

General Description

2-Methyl-3-nitrothiophene-5-carboxylic Acid, also known as MNTCA, is a chemical compound with a molecular formula of C7H5NO4S. It is a derivative of thiophene and contains a nitro group and carboxylic acid functionality. MNTCA is commonly used in organic synthesis and pharmaceutical research as a building block for producing new compounds with potential medicinal properties. Its unique structure makes it a valuable intermediate in the development of various drugs such as antiviral and anticancer agents. Additional applications of MNTCA include its role as a ligand in coordination chemistry and its use in the production of dyes and pigments.

InChI:InChI=1/C6H5NO4S/c1-3-4(7(10)11)2-5(12-3)6(8)9/h2H,1H3,(H,8,9)

Upstream product

• 1918-79-2 2-methylthiophene-5-carboxylic acid 
• 98-03-3 thiophene-2-carbaldehyde 
• 554-14-3 2-Methylthiophene 
• 7697-37-2 nitric acid 
• 108-24-7 acetic anhydride 

Downstream Products

• 78771-28-5 2-Methyl-3,5-dinitrothiophene 
• 5415-99-6 4-ethyl aminobutyric acid 
• 66117-23-5 ethyl 5-methyl-4-nitrothiophene-2-carboxylate 
• 17286-18-9 5-methyl-4-nitro-thiophene-2-carboxylic acid benzyl ester 
• 56921-01-8 5-methyl-4-nitro-thiophene-2-carboxylic acid methyl ester 
• 58963-75-0 3-nitrothiophene-2-carbaldehyde 
• 95577-06-3 5-Benzylsulfanyl-4-oxo-hexanoic acid 
• 749261-96-9 4H-thieno[3,2-b]pyrrole-2-carboxylic acid methyl ester 
• 1001608-59-8 5-[2-(2-fluoro-phenyl)-quinolin-6-yl]-4H-thieno[3,2-b]pyrrole-2-carboxylic acid methyl ester 

Relevant articles and documents

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THIENOPYRROLE COMPOUNDS AS S-NITROSOGLUTATHIONE REDUCTASE INHIBITORS

The present disclosure is directed to compounds of formula (Ib) and pharmaceutically acceptable salts thereof, wherein A, Q, R1, R3, R5 and m are as defined herein, which are active as inhibitors of S-Nitrosoglutathione re

FLUORO-SUBSTITUTED INHIBITORS OF D-AMINO ACID OXIDASE

This invention provides novel inhibitors of the enzyme D-amino acid oxidase as well as pharmaceutical compositions including the compounds of the invention. The invention also provides methods for the treatment and prevention of neurological disorders, such as neuropsychiatric and neurodegenerative diseases, as well as pain, ataxia and convulsion. The compounds of the invention have the general structure: wherein A is NH or S. Q is a member selected from CR1 and N. X and Y are members independently selected from O, S, CR2, N and NH. R1, R2 and R4 are members independently selected from H and F, provided that at least one member selected from R1, R2 and R4 is F. R6 is a member selected from O?X+ and OH, wherein X+ is a positive ion, which is a member selected from inorganic positive ions and organic positive ions.