3608-58-0 Usage
Description
3'-Deoxyguanosine is a derivative of guanosine, a nucleoside that plays a crucial role in various biological processes. As a ligand, it can form complexes with enzymes such as purine nucleoside phosphorylase and receptors, making it a valuable tool for studying structure-activity relationships. 3'-DEOXYGUANOSINE is also known for its potential as an anti-amoebic agent and its ability to selectively impair transcription. With its solid chemical properties, 3'-deoxyguanosine offers a range of applications across different industries.
Uses
Used in Pharmaceutical Applications:
3'-Deoxyguanosine is used as a research compound for studying the interactions between ligands, enzymes, and receptors. Its ability to form complexes with purine nucleoside phosphorylase and receptors helps researchers understand the underlying mechanisms of various biological processes and develop targeted therapies.
Used in Antimicrobial Applications:
As a potential anti-amoebic agent, 3'-deoxyguanosine is used in the development of treatments for amoebic infections. Its ability to selectively impair transcription makes it a promising candidate for targeting and disrupting the life cycle of amoebic parasites.
Used in Biochemical Research:
3'-Deoxyguanosine is used as a tool in biochemical research to investigate the structure-activity relationships of various compounds. Its interaction with enzymes and receptors provides valuable insights into the design and optimization of new drugs and therapeutic agents.
Used in Drug Development:
3'-DEOXYGUANOSINE's ability to selectively impair transcription makes it a valuable asset in the development of new drugs targeting specific genetic pathways. Researchers can use 3'-deoxyguanosine to study the effects of transcription inhibition on cellular processes and develop novel therapeutic strategies for various diseases.
Check Digit Verification of cas no
The CAS Registry Mumber 3608-58-0 includes 7 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 4 digits, 3,6,0 and 8 respectively; the second part has 2 digits, 5 and 8 respectively.
Calculate Digit Verification of CAS Registry Number 3608-58:
(6*3)+(5*6)+(4*0)+(3*8)+(2*5)+(1*8)=90
90 % 10 = 0
So 3608-58-0 is a valid CAS Registry Number.
3608-58-0Relevant articles and documents
Synthesis of 2′,3′-dideoxypurinenucleosides via the palladium catalyzed reduction of 9-(2,5-di-O-acetyl-3-bromo-3-deoxy-β-D-xylofuranosyl)purine derivatives
Shiragami, Hiroshi,Amino, Yusuke,Honda, Yutaka,Arai, Masayuki,Tanaka, Yasuhiro,Iwagami, Hisao,Yukawa, Toshihide,Izawa, Kunisuke
, p. 31 - 45 (1996)
Practical method to produce 2′,3′-dideoxypurinenucleosides from 9-(2,5-di-O-acetyl-3-bromo-3-deoxy-β-D-xylofuranosyl)purines (1) was developed. High ratio of 2′,3′-dideoxynucleoside to 3′-deoxyribonucleoside was obtained by selecting the reaction conditions (solvent, pH and/or base), or changing 2′-acyloxy leaving group. The reaction mechanism was studied by deuteration experiments of 1a and 1-(3,5-di-O-acetyl-2-bromo-2-deoxy-β-D-ribofuranosyl)thymine (12).