36085-73-1 Usage
Description
B-HT 920 DIHYDROCHLORIDE is a potent agonist of dopamine 2 (D2) receptors, with a high affinity (Ki = 5.8 nM) and selectivity for D2 over D3 and D4 receptors. It also acts as an agonist of α2-adrenergic receptors and an antagonist of serotonin-3 (5-HT3; Ki = 0.35 μM) receptors. B-HT 920 DIHYDROCHLORIDE exhibits neuroprotective and regenerative effects in animal models of Parkinson's disease. It is a light yellow solid.
Uses
Used in Pharmaceutical Industry:
B-HT 920 DIHYDROCHLORIDE is used as an antiparkinson reagent for its neuroprotective and regenerative effects in animal models of Parkinson's disease. It modulates the dopaminergic system, which is crucial for the treatment of Parkinson's disease, by acting as an agonist of dopamine 2 (D2) receptors.
Used in Research Applications:
B-HT 920 DIHYDROCHLORIDE is used as a research tool for studying the roles of dopamine 2 (D2) receptors, α2-adrenergic receptors, and serotonin-3 (5-HT3) receptors in various neurological and psychiatric conditions. Its agonistic and antagonistic properties make it a valuable compound for understanding receptor interactions and developing new therapeutic strategies.
Biological Activity
Dopamine D 2 receptor agonist, α 2 -adrenoceptor agonist and 5-HT 3 receptor antagonist. Displays antiParkinsonian activity.
Check Digit Verification of cas no
The CAS Registry Mumber 36085-73-1 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 3,6,0,8 and 5 respectively; the second part has 2 digits, 7 and 3 respectively.
Calculate Digit Verification of CAS Registry Number 36085-73:
(7*3)+(6*6)+(5*0)+(4*8)+(3*5)+(2*7)+(1*3)=121
121 % 10 = 1
So 36085-73-1 is a valid CAS Registry Number.
InChI:InChI=1/C10H15N3S.2ClH/c1-2-5-13-6-3-8-9(4-7-13)14-10(11)12-8;;/h2H,1,3-7H2,(H2,11,12);2*1H