3616-57-7

Basic information

• Product Name: 2,2-Diethoxytriethylamine
• Synonyms: Ethanamine, 2,2-diethoxy-N,N-diethyl-;2,2-DIETHOXY-N,N-DIETHYL-ETHANAMINE;2,2-DIETHOXYTRIETHYLAMINE;DIETHYLAMINOACETALDEHYDE DIETHYL ACETAL;2,2-diethoxyethyl(diethyl)amine;(Diethylamino)acetaldehydediethylacetale;2,3-Diethoxytriethylamine;DIETHYLAMINOACETALDEHYDE DIETHYL
• CAS NO: 3616-57-7
• Molecular Formula: C₁₀H₂₃NO₂
• Molecular Weight: 189.3
• EINECS: 222-801-6
• Mol File: 3616-57-7.mol
• Article Data: 4

Chemical Properties

• Boiling Point: 194-195 °C(lit.)
• Flash Point: 149 °F
• Appearance: clear yellow to brown liquid
• Density: 0.85 g/mL at 25 °C(lit.)
• Vapor Pressure: 0.44mmHg at 25°C
• Refractive Index: n20/D 1.4189(lit.)
• PKA: 10.21±0.25(Predicted)
• CAS DataBase Reference: 2,2-Diethoxytriethylamine(CAS DataBase Reference)
• NIST Chemistry Reference: 2,2-Diethoxytriethylamine(3616-57-7)
• EPA Substance Registry System: 2,2-Diethoxytriethylamine(3616-57-7)

Safety Data

• Hazard Codes: Xi
• Statements: 36/37/38
• Safety Statements: 26-36/37/39-37/39
• WGK Germany: 3
• Hazardous Substances Data: 3616-57-7(Hazardous Substances Data)

Usage

Chemical Properties

CLEAR YELLOW TO BROWN LIQUID

InChI:InChI=1/C10H23NO2/c1-5-11(6-2)9-10(12-7-3)13-8-4/h10H,5-9H2,1-4H3/p+1

Upstream product

• 64-17-5 ethanol 
• 121-44-8 triethylamine 
• 109-89-7 diethylamine 
• 621-62-5 chloroacetaldehyde diethyl acetal 
• 2032-35-1 Bromoacetaldehyde diethyl acetal 

Downstream Products

• 123367-22-6 (E)-N,N-dimethyl-2-(4-nitro-1-oxidopyridin-3-yl)ethenamine 
• 98398-26-6 diethyl-(2,2-diphenyl-ethyl)-amine 

Relevant articles and documents

Preparation method of novel quinazoline drug side chain

The invention discloses a preparation method of a novel quinazoline drug side chain, which comprises the following steps: taking bromoacetaldehyde diethyl acetal and diethylamine as raw materials, carrying out condensation reaction, extracting, drying, concentrating, rectifying and the like to obtain a condensation compound, and hydrolyzing, extracting and concentrating the condensation compound to obtain 2-diethyl amino acetaldehyde. The raw materials are cheap and easy to obtain, the reaction condition is mild, the operation is safe and simple, the product quality is good, and industrial production is facilitated.

Iodine-Catalyzed Oxidative Rearrangement of Amines to α-Amino Acetals and α-Amino Aldehydes

A protocol for iodine-catalyzed oxidative rearrangement of tertiary and secondary amines has been developed. This metal-free protocol provides an atom-economical, efficient access to synthetically useful α-amino acid derivatives from readily available acyclic and cyclic tertiary or secondary amines. (Figure presented.).