36176-88-2

Basic information

• Product Name: Benzenesulfonamide, N-[(4-bromophenyl)methylene]-
• Synonyms: N-(4-bromobenzylidene)benzenesulfonamide;N-(phenylsulfonyl)-p-bromobenzaldehyde imine;N-phenylsulfonyl-p-bromobenzylideneamine;N-p-bromobenzylidenebenzenesulfonamide;Benzenesulfonamide,N-[(4-bromophenyl)methylene]
• CAS NO: 36176-88-2
• Molecular Formula: C13H10BrNO2S
• Molecular Weight: 324.198
• Mol File: 36176-88-2.mol
• Article Data: 16

Chemical Properties

• CAS DataBase Reference: Benzenesulfonamide, N-[(4-bromophenyl)methylene]-(CAS DataBase Reference)
• NIST Chemistry Reference: Benzenesulfonamide, N-[(4-bromophenyl)methylene]-(36176-88-2)
• EPA Substance Registry System: Benzenesulfonamide, N-[(4-bromophenyl)methylene]-(36176-88-2)

Safety Data

• Hazardous Substances Data: 36176-88-2(Hazardous Substances Data)

Upstream product

• 87301-29-9 N-(phenylsulfonylimino)-phenyl-λ³-iodane 
• 1122-91-4 4-bromo-benzaldehyde 
• 10504-95-7 N-(2-bromobenzyl)-4-methybenzenesulfonamide 
• 2845-62-7 benzenesulphonyl isocyanate 
• 98-10-2 benzenesulfonamide 
• 34421-94-8 4-bromobenzaldehyde diethyl acetal 
• 61945-92-4 N,N'-di(phenylsulfonyl)selenium diimide 
• 71877-43-5 N-phenylsulfonyl-N'-acetylselenium diimide 
• 52867-18-2 N-phenylsulphonyl-Se,Se-diphenylselenimide 

Downstream Products

• 1345268-85-0 C₁₃H₁₀BrNO₃S 
• 10504-95-7 N-(2-bromobenzyl)-4-methybenzenesulfonamide 
• 1244568-25-9 N-((4-chlorophenyl)(1H-pyrrol-2-yl)methyl)benzenesulfonamide 
• 1236009-93-0 N-(benzenesulfonyl)-2-(4-bromobenzyl)aziridine 

Relevant articles and documents

Synthesis of Diversely Substituted Imidazolidines via [3+2] Cycloaddition of 1,3,5-Triazinanes with Donor-Acceptor Aziridines and Their Anti-Tumor Activity

A Y(OTf)3-catalyzed [3+2] cycloaddition of 1,3,5-triazinanes with donor-acceptor aziridines has been developed, accessing diversely substituted imidazolidines high efficiency. Mechanistic investigations support the formation of imidazolidines through an SN1-like pathway. Furthermore, these imidazolidines exhibit promising anti-tumor activity against a series of human cancer cell lines. (Figure presented.).

Silica-supported zinc chloride (ZnCl2/SiO2)-induced efficient protocol for the synthesis of N-sulfonyl imines and 2-Arylbenzothiazole

A straightforward strategy for the synthesis of N-sulfonyl imine derivatives from sulfonamides and aryl aldehydes utilizing Silica-supported zinc chloride (ZnCl2/SiO2, silzic) as a catalyst under solvent-free conditions has been developed. 2-Arylbenzothiazole derivatives were also synthesized by the reaction of 2-aminothiophenol with aryl aldehydes under the same conditions. This procedure has advantages of high yields, mild reaction condition, simple procedure, low cost, and simplicity of workup. The catalyst has the same efficiency on its reuse up to three times.

Formation of: N -sulfonyl imines from iminoiodinanes by iodine-promoted, N-centered radical sulfonamidation of aldehydes

A mild and operationally convenient formation of synthetically valuable N-sulfonyl imines from a range of aryl aldehydes by reaction with iminoiodinanes (PhINZ) and I2 has been developed. According to mechanistic experiments described within, the reaction is speculated to proceed through an unconventional light-promoted, N-centered radical (NCR) pathway involving a N,N-diiodosulfonamide reactive species. This method not only provides a new pathway toward the production of activated imines, but also serves as an example of a non-traditional means of carbonyl activation via an NCR species.