3621-71-4Relevant articles and documents
Synthesis of 5-hydroxy hydantoins via a tandem process
Meza-León, Rosa Luisa,Bernès, Sylvain,Cortés-López, Guadalupe Nallely,Mastranzo, Virginia M.,Sosa-Rivadeneyra, Martha,Sartillo-Piscil, Fernando
, p. 4232 - 4234 (2016)
An efficient entry to 5-hydroxyhydantoin derivatives is reported. The reaction of α-ketoacids with commercially available carbodiimides under mild conditions, and in the presence of visible light, induces the rearrangement of an O-acyl urea, and eventuall
Reaction of 5-hydroxyimino-1,3-dioxine-4,6-dione (isonitroso meldrum's acid) with carbodiimides to give parabanic acids
Katagiri, Nobuya,Morishita, Yoshihiro,Kaneko, Chikara
, p. 503 - 508 (2007/10/03)
Reaction of 5-hydroxyimino-1,3-dioxine-4,6-dione (isonitroso Meldrum's Acid) with carbodiimides gave cyanoformamide derivatives in quantitative yields, which cyclized to iminoparabanic acids and parabanic acids under basic and acidic conditions, respectively.
Pharmaceutical composition containing an imidazolidinetrione derivative or pharmaceutically acceptable salt thereof
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, (2008/06/13)
Pharmaceutical compositions containing imidazolidinetrione derivatives or pharmaceutically acceptable salts thereof having hypoglycemic and hypolipidemic effects. The compositions comprise as an active ingredient at least one imidazolidinetrione derivative of the formula: STR1 wherein each of R1 and R2, which may be the same or different, is hydrogen, an alkyl group, a cycloalkyl group or STR2 and each of R3 and R4, which may be the same or different, is hydrogen, halogen, a nitro group, a lower alkyl group or a lower alkoxy group.
