36220-29-8

Basic information

• Product Name: 2-(4-chloro-2-methyl-phenoxy)ethanol
• Synonyms: 2-(4-chloro-2-methyl-phenoxy)ethanol;MCPE
• CAS NO: 36220-29-8
• Molecular Formula: C₉H₁₁ClO₂
• Molecular Weight: 186.64
• Mol File: 36220-29-8.mol
• Article Data: 4

Chemical Properties

• Boiling Point: 294.5°C at 760 mmHg
• Flash Point: 131.9°C
• Appearance: /
• Density: 1.198g/cm³
• Vapor Pressure: 0.000735mmHg at 25°C
• Refractive Index: 1.539
• CAS DataBase Reference: 2-(4-chloro-2-methyl-phenoxy)ethanol(CAS DataBase Reference)
• NIST Chemistry Reference: 2-(4-chloro-2-methyl-phenoxy)ethanol(36220-29-8)
• EPA Substance Registry System: 2-(4-chloro-2-methyl-phenoxy)ethanol(36220-29-8)

Safety Data

• Hazardous Substances Data: 36220-29-8(Hazardous Substances Data)

Usage

InChI:InChI=1/C9H11ClO2/c1-7-6-8(10)2-3-9(7)12-5-4-11/h2-3,6,11H,4-5H2,1H3

Upstream product

• 75-21-8 oxirane 
• 1570-64-5 2-methyl-4-chlorophenol 
• 107-07-3 2-chloro-ethanol 
• 6161-86-0 2-methylphenoxyethanol 
• 540-51-2 2-bromoethanol 

Downstream Products

• 1254734-39-8 R,S-2-[(4-chloro-2-methylphenoxy)ethyl]amino-1-phenylethan-1-ol 
• 26378-21-2 (4-chloro-2-methylphenoxy)ethyl bromide 
• 1254734-34-3 R,S-1-[(4-chloro-2-methylphenoxy)ethyl]aminopropan-2-ol 
• 1254734-35-4 R,S-2-[(4-chloro-2-methylphenoxy)ethyl]aminopropan-1-ol 
• 1254734-36-5 R,S-1-[(4-chloro-2-methylphenoxy)ethyl]aminobutan-2-ol 
• 1254734-37-6 R,S-2-[(4-chloro-2-methylphenoxy)ethyl]aminobutan-1-ol 
• 1254734-38-7 2-[(4-chloro-2-methylphenoxy)ethyl]amino-2-methylpropan-1-ol 
• 94-74-6 MCPA 
• 3653-48-3 sodium 2-methyl-4-chlorophenoxyacetate 
• 99984-24-4 1-(4-chloro-2-methyl-phenoxy)-2-trichloroacetoxy-ethane 
• 119015-89-3 dichlorophosphoric acid-[2-(4-chloro-2-methyl-phenoxy)-ethyl ester] 
• 100120-21-6 1-(4-chloro-2-methyl-phenoxy)-2-(2,2-dichloro-propionyloxy)-ethane 

Relevant articles and documents

PYRIDIN-3-YL ACETIC ACID DERIVATIVES AS INHIBITORS OF HUMAN IMMUNODEFICIENCY VIRUS REPLICATION

Disclosed are compounds of Formula I, including pharmaceutically acceptable salts, pharmaceutical compositions comprising the compounds, methods for making the compounds and their use in inhibiting HIV integrase and treating those infected with HIV or AIDS.

Synthesis and evaluation of anticonvulsant activity of some N-[(4-Chlor-2-methylphenoxy)ethyl]- and N-[(4-Chlor-2-methylphenoxy)acetyl] aminoalkanols

A new series of N-(4-chlor-2-methylphenoxy)ethyl- (1-6) and N-(4-chlor-2-methylphenoxy)acetylaminoalkanols (7-10) has been synthesized for evaluation of their anticonvulsant activity. Pharmacological tests included maximal electroshock seizure (MES) and subcutaneous pentylenetetrazole seizure (ScMet) assays, as well as rotarod for neurotoxicity (TOX) and were performed in mice i.p. and rats p.o. The activity of the compounds in the group was various, and the most active compound in mice was R,S-1N-[(4-chlor-2-methylphenoxy) ethyl]aminopropan-2-ol, revealing 100% activity in MES test at 30 mg/kg b.w., 0.5 h after administration without toxicity at the same dose and time. In rats (p.o.), the most active compound was 2N-[(4-chlor-2-methylphenoxy)ethyl]amino-2- methylpropan-1-ol, revealing 25% activity in MES at 30 mg/kg b.w. 0.5 and 1 h after administration.