36242-53-2

Basic information

• Product Name: Benzenamine, 5-methoxy-2-nitro-N-phenyl-
• CAS NO: 36242-53-2
• Molecular Formula: C13H12N2O3
• Molecular Weight: 244.25
• Mol File: 36242-53-2.mol
• Article Data: 5

Chemical Properties

• CAS DataBase Reference: Benzenamine, 5-methoxy-2-nitro-N-phenyl-(CAS DataBase Reference)
• NIST Chemistry Reference: Benzenamine, 5-methoxy-2-nitro-N-phenyl-(36242-53-2)
• EPA Substance Registry System: Benzenamine, 5-methoxy-2-nitro-N-phenyl-(36242-53-2)

Safety Data

• Hazardous Substances Data: 36242-53-2(Hazardous Substances Data)

Upstream product

• 108-86-1 bromobenzene 
• 16133-49-6 5-methoxy-2-nitroaniline 
• 591-50-4 iodobenzene 
• 108805-66-9 3-methoxy-N-nitrosodiphenylamine 
• 62-53-3 aniline 
• 28987-59-9 3-chloro-4-nitroanisole 
• 98447-30-4 2-bromo-4-methoxy-1-nitrobenzene 
• 108805-69-2 5-methoxy-2-nitroso-N-phenylaniline 

Downstream Products

• 22316-48-9 N-carbethoxy acetyl 2-nitro 5-methoxy diphenylamine 
• 82582-23-8 4-methoxy-N²-phenylbenzene-1,2-diamine 

Relevant articles and documents

Ni-Catalyzed Dual C-H Annulation of Benzimidazoles with Alkynes for Synthesis of π-Extended Heteroarenes

Transition metal catalyzed dual C-H activation and annulation with alkynes was an attractive protocol to construct polycyclic π-extended structures. However, most of them were dominated by noble metal catalysts. Disclosed herein was the study of base-metal Ni-catalysis for dual C-H annulation of N-aromatic imidazole, which produced a range of desired polycyclic aza-quinolines in 48-95% yields. The use of bifunctional phosphine oxide ligand proved to be critical for success.

New Benzimidazole Synthesis

Thermal or acid catalyzed cyclization of several N-(N-arylbenzimidoyl)-1,4-benzoquinoneimines 2 affords 1-aryl-6-hydroxy-2-phenylbenzimidazoles 3 in fairly good yields.Structural proofs and kinetic support for the reaction mechanism are given.

New synthetic routes for 8-methoxyellipticine

-