3625-06-7

Basic information

• Product Name: MEBEVERINE
• Synonyms: Mebeverine [inn:ban];Mebeverinum;4-(ethyl(1-(4-Methoxyphenyl)propan-2-yl)aMino)butyl 3,4-diMethoxybenzoate;3,4-dimethoxy-benzoicaci4-(ethyl(2-(4-methoxyphenyl)-1-methylethyl)amin;o)butylester;veratricacid,4-((ethyl(p-methoxy-alpha-methylphenethyl))amino)butylester;MEBEVERINE;3,4-Dimethoxybenzoic acid 4-[ethyl[2-(4-methoxyphenyl)-1-methylethyl]amino]butyl ester
• CAS NO: 3625-06-7
• Molecular Formula: C₂₅H₃₅NO₅
• Molecular Weight: 429.55
• EINECS: 222-830-4
• Mol File: 3625-06-7.mol
• Article Data: 0

Chemical Properties

• Melting Point: 129-131 °C
• Boiling Point: 543.8 °C at 760 mmHg
• Flash Point: 282.7 °C
• Appearance: /
• Density: 1.074 g/cm³
• Vapor Pressure: 6.92E-12mmHg at 25°C
• Refractive Index: 1.529
• PKA: 9.51±0.50(Predicted)
• CAS DataBase Reference: MEBEVERINE(CAS DataBase Reference)
• NIST Chemistry Reference: MEBEVERINE(3625-06-7)
• EPA Substance Registry System: MEBEVERINE(3625-06-7)

Safety Data

• Hazardous Substances Data: 3625-06-7(Hazardous Substances Data)

Usage

Uses

Relaxant (smooth muscle).

Therapeutic Function

Spasmolytic

InChI:InChI=1/C25H35NO5/c1-6-26(19(2)17-20-9-12-22(28-3)13-10-20)15-7-8-16-31-25(27)21-11-14-23(29-4)24(18-21)30-5/h9-14,18-19H,6-8,15-17H2,1-5H3

Synthetic route

mebeverine (3625-06-7) → 4-(ethyl [2-(4-methoxyphenyl)-1-methylethyl]amino)butan-1-ol (14367-47-6, 14664-74-5)

Conditions	Yield
With sodium hydroxide In methanol at 45℃; for 12h;

mebeverine (3625-06-7) → Veratric acid (93-07-2)

Conditions	Yield
Stage #1: mebeverine With sodium hydroxide In methanol at 45℃; for 12h; Stage #2: With hydrogenchloride; water

Downstream Products

• 14367-47-6 4-(ethyl [2-(4-methoxyphenyl)-1-methylethyl]amino)butan-1-ol 
• 93-07-2 Veratric acid