362613-34-1

Basic information

• Product Name: tris[3-(N-methylamino)propyl]amine
• CAS NO: 362613-34-1
• Molecular Weight: 230.397
• Mol File: 362613-34-1.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: tris[3-(N-methylamino)propyl]amine(CAS DataBase Reference)
• NIST Chemistry Reference: tris[3-(N-methylamino)propyl]amine(362613-34-1)
• EPA Substance Registry System: tris[3-(N-methylamino)propyl]amine(362613-34-1)

Safety Data

• Hazardous Substances Data: 362613-34-1(Hazardous Substances Data)

Upstream product

• 1403989-31-0 tri-tert-butyl (nitrilotris(propane-3,1-diyl))tricarbamate 
• 4963-47-7 Tris(3-aminopropyl)amine 
• 14002-34-7 tripropanolamine 
• 7528-78-1 tris(2-cyanoethyl)amine 
• 362613-32-9 tris[3-(ethoxycarbonylamino)propyl]amine 
• 74-89-5 methylamine 
• 362613-33-0 tris(3-bromopropyl)amine 

Relevant articles and documents

Flexible covalent tripods in nonadentate podands: Synthesis of tris[3-(6-diethylcarbamoylpyridine-2-carboxamido)propyl]amine and its complexing properties with trivalent lanthanides

The nonadentate podand tris[3-(6-diethylcarbamoylpyridine-2-carboxamido)propyl]amine (L14) is prepared according to a multistep strategy using the flexible tris(3-(N-methylamino)propyl)amine (Me-TRPN) covalent tripod. L14 exists as a statistical mixture of four conformers in solution whose distribution is slightly affected by protonation of the apical nitrogen atom in [L14 + H]+. The pKa value depends on the length of the spacer separating the apical nitrogen and the appended electron-withdrawing tertiary amide groups, and increases by three orders of magnitude when going from the Me-TREN tripod in [L13 + H]+ (ethylene spacer) to Me-TRPN in [L14 + H]+ (trimethylene spacer). Reactions of L14 and [L14 + H]+ with Ln(ClO4)3 (Ln = La-Lu) produce flexible and poorly stable 1:1 podates [Ln(L14)]3+ and [Ln(L14 + H)]4+ in which the terdentate chelating binding units exhibit partial dynamic on-off complexation equilibria. Comparisons of structural and thermodynamic data for [Ln(Ln)]3+ (n = 13 or 14) in solution point to a drastic decrease of the molecular organisation of the podand when the constrained Me-TREN tripod is replaced by the elongated Me-TRPN tripod in nine-co-ordinate lanthanide podates, a crucial limiting factor for the design of supramolecular lanthanide complexes with predetermined properties.