363-81-5 Usage
Chemical Properties
COLORLESS TO LIGHT GREY CRYSTALS
Uses
Different sources of media describe the Uses of 363-81-5 differently. You can refer to the following data:
1. 2,4,6-Trifluoroaniline was used in the synthesis of 3-nitro-2,4,6 -trifluoroacetanilide; eries of N?-phenyl-N-(1- phenyl cyclopentyl)-methyl ureas and 4-substituted 2,6-difluoro N-aryl pyridinones.
2. 2,4,6-Trifluoroaniline was used in the synthesis of:3-nitro-2,4,6 -trifluoroacetanilideseries of N′-phenyl-N-(1- phenyl cyclopentyl)-methyl ureas4-substituted 2,6-difluoro N-aryl pyridinones
Check Digit Verification of cas no
The CAS Registry Mumber 363-81-5 includes 6 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 3 digits, 3,6 and 3 respectively; the second part has 2 digits, 8 and 1 respectively.
Calculate Digit Verification of CAS Registry Number 363-81:
(5*3)+(4*6)+(3*3)+(2*8)+(1*1)=65
65 % 10 = 5
So 363-81-5 is a valid CAS Registry Number.
InChI:InChI=1/C6H4FNO/c7-6-5(4-9)2-1-3-8-6/h1-4H
363-81-5Relevant articles and documents
Divergent Late-Stage (Hetero)aryl C?H Amination by the Pyridinium Radical Cation
Ham, Won Seok,Hillenbrand, Julius,Jacq, Jér?me,Genicot, Christophe,Ritter, Tobias
supporting information, p. 532 - 536 (2019/01/04)
(Hetero)arylamines constitute some of the most prevalent functional molecules, especially as pharmaceuticals. However, structurally complex aromatics currently cannot be converted into arylamines, so instead, each product isomer must be assembled through a multistep synthesis from simpler building blocks. Herein, we describe a late-stage aryl C?H amination reaction for the synthesis of complex primary arylamines that other reactions cannot access directly. We show and rationalize through a mechanistic analysis the reasons for the wide substrate scope and the constitutional diversity of the reaction, which gives access to molecules that would not have been readily available otherwise.
