3641-10-9 Usage
Description
3-Cyano-1,2,4-triazole is a cyano-substituted triazole compound known for its inhibitory effects on cathepsin K, an enzyme involved in bone resorption and immune response regulation. This unique property makes it a valuable subject for scientific research and potential applications in various fields.
Uses
Used in Pharmaceutical Research:
3-Cyano-1,2,4-triazole is used as a research compound for studying the electrophilicity and reactivity of diverse nitrile-containing compounds. Its correlation to the mechanism-of-action is of particular interest, as understanding these properties can lead to the development of new therapeutic agents.
Used in Enzyme Inhibition Studies:
In the field of biochemistry, 3-Cyano-1,2,4-triazole is utilized as an inhibitor of cathepsin K, providing insights into the enzyme's role in various biological processes. This application aids in the exploration of potential treatments for conditions related to bone metabolism and immune system function.
Used in Material Science:
3-Cyano-1,2,4-triazole's reactivity and electrophilicity also make it a candidate for use in material science research. Its properties can be harnessed to develop new materials with specific characteristics, such as enhanced stability or reactivity, for various industrial applications.
Check Digit Verification of cas no
The CAS Registry Mumber 3641-10-9 includes 7 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 4 digits, 3,6,4 and 1 respectively; the second part has 2 digits, 1 and 0 respectively.
Calculate Digit Verification of CAS Registry Number 3641-10:
(6*3)+(5*6)+(4*4)+(3*1)+(2*1)+(1*0)=69
69 % 10 = 9
So 3641-10-9 is a valid CAS Registry Number.
InChI:InChI=1/C3H2N4/c4-1-3-5-2-6-7-3/h2H,(H,5,6,7)
3641-10-9Relevant articles and documents
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Witkowski et al.
, p. 935 (1973)
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Chemoenzymatic method of 1,2,4-triazole nucleoside synthesis: Possibilities and limitations
Konstantinova,Chudinov,Fateev,Matveev,Zhurilo,Shvets,Miroshnikov
, p. 53 - 71 (2013/04/10)
Possibilities and limitations of chemoenzymatic synthesis of novel structural analogues of an antiviral preparation of Ribavirin (1-β-D-ribofuranosyl-1,2,4-triazole-3-carboxamide) were established. A synthesis of various amides of 1H-1,2,4-triazole-3-carboxylic acid and its 5-substituted analogues - potential substrates of purine nucleoside phosphorylase - has been described. Comparative efficiency of preparation methods of these amides, as well as the methods of introduction of functional groups to the C5 position of heterocyclic system, were investigated. Novel analogues of Ribavirin containing various substitutes in the carboxamide group were synthesized. A biotechnological method was developed for the preparation of 1-β-D-ribofuranozyl-1,2,4-triazole-3-carbonitryl, an intermediate in the synthesis of Viramidine, the modern analogue of Ribavirin.
