364386-48-1

Basic information

• Product Name: (1R,2S)-N-tert-butoxycarbonyl-2-[2-(4-methoxybenzylamino)-6-methoxyquinazolin-4-yl]aminocyclohexylamine
• Synonyms: (1R,2S)-N-tert-butoxycarbonyl-2-[2-(4-methoxybenzylamino)-6-methoxyquinazolin-4-yl]aminocyclohexylamine
• CAS NO: 364386-48-1
• Molecular Weight: 507.633
• Mol File: 364386-48-1.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: (1R,2S)-N-tert-butoxycarbonyl-2-[2-(4-methoxybenzylamino)-6-methoxyquinazolin-4-yl]aminocyclohexylamine(CAS DataBase Reference)
• NIST Chemistry Reference: (1R,2S)-N-tert-butoxycarbonyl-2-[2-(4-methoxybenzylamino)-6-methoxyquinazolin-4-yl]aminocyclohexylamine(364386-48-1)
• EPA Substance Registry System: (1R,2S)-N-tert-butoxycarbonyl-2-[2-(4-methoxybenzylamino)-6-methoxyquinazolin-4-yl]aminocyclohexylamine(364386-48-1)

Safety Data

• Hazardous Substances Data: 364386-48-1(Hazardous Substances Data)

Upstream product

• 364386-47-0 (1R,2S)-N-tert-butoxycarbonyl-2-(2-chloro-6-methoxyquinazolin-4-yl)aminocyclohexylamine 
• 76144-87-1 2,2'-bis-(diphenylphosphino)-1,1'-binaphthyl 
• 2393-23-9 4-methoxy-benzylamine 

Relevant articles and documents

Heterocycle derivatives and drugs

There is provided an excellent novel analgesic having an analgesic effect which is effective widely against a pain including a chronic pain or an allodynia accompanied with herpes zoster by acting on a nociceptin receptor. The present invention relates to a compound represented by the following formula: or a salt thereof. In the formula, X and Y are same or different and each represents a nitrogen atom or CH; R1 represents a hydrogen atom or alkyl and the like; A1 and A2 are same or different and each represents a single bond or a divalent aliphatic hydrocarbon group; Q represents a single bond, cycloalkylene group, phenylene group or divalent heterocyclic group; R2A, R2B, R2C and R2D are same or different and each represents a hydrogen atom, alkyl or phenyl; E represents a ethenylene group or —NRCO— (in which R is hydrogen or alkyl) and the like; R3 represents a phenyl group or a heterocyclic group; R4 and R5 are same or different and each represents a hydrogen atom, alkyl, alkoxy, aralkyloxy, halogen, nitro, hydroxy, alkoxycarbonyl, —NR6R7 (in which R6 and R7 are same or different and each represents a hydrogen atom or alkyl) and the like.