36468-53-8

Basic information

• Product Name: beta-D-Ribofuranose (9CI)
• Synonyms: beta-D-Ribofuranose (9CI);(2R,3R,4S,5R)-5-(hydroxyMethyl)tetrahydrofuran-2,3,4-triol
• CAS NO: 36468-53-8
• Molecular Formula: C₅H₁₀O₅
• Molecular Weight: 150.1299
• Product Categories: CARBOHYDRATE
• Mol File: 36468-53-8.mol
• Article Data: 85

Chemical Properties

• Boiling Point: 375.4±42.0 °C(Predicted)
• Appearance: /
• Density: 1.681±0.06 g/cm3(Predicted)
• PKA: 12.16±0.70(Predicted)
• CAS DataBase Reference: beta-D-Ribofuranose (9CI)(CAS DataBase Reference)
• NIST Chemistry Reference: beta-D-Ribofuranose (9CI)(36468-53-8)
• EPA Substance Registry System: beta-D-Ribofuranose (9CI)(36468-53-8)

Safety Data

• Hazardous Substances Data: 36468-53-8(Hazardous Substances Data)

Usage

General Description

Beta-D-ribofuranose (9CI) is a chemical compound that belongs to the group of ribofuranoses, which are sugar molecules derived from ribofuranose, a five-carbon sugar. It is often used in the formation of DNA and RNA, as well as in other biological processes. beta-D-Ribofuranose (9CI) is known for its role in maintaining the structural integrity of nucleic acids and for its involvement in energy production within cells. It is also used in the synthesis of various pharmaceuticals and in biochemical research. As a carbohydrate derivative, beta-D-ribofuranose (9CI) plays an essential role in the biochemistry of living organisms and is the subject of ongoing research in the fields of molecular biology and medicine.

Upstream product

• 524-69-6 adenine xyloside 
• 20031-21-4 1,2-O-isopropylidene-α-D-xylose 
• 1824-96-0 methyl α-D-xylofuranoside 
• 141923-44-6 α-Ara(f)-(1->3)-β-Xyl(p)-(1->4)-Xyl(p) 
• 68768-32-1 3-methylguanosine 
• 1341-23-7 1-(β-D-ribofuranosyl)-nicotinamide 
• 572-30-5 3,3',4',5,7-pentahydroxyflavone 3-O-arabogluocopyranoside 
• 5536-17-4 arabinosyl adenine 
• 3228-71-5 9-(α-D-arabinofuranosyl)adenine 
• 2280-44-6 D-Glucose 
• 50-00-0 formaldehyd 
• 58-61-7 adenosine 
• 7473-45-2 1-O-methyl-D-ribofuranose 
• 52485-92-4 methyl α-D-ribofuranoside 

Downstream Products

• 53829-60-0 1,2-O-isopropylidene-α-D-xylofuranose-3,5-phenylboronate 
• 98-01-1 furfural 
• 64-18-6 formic acid 
• 79-14-1 glycolic Acid 
• 849585-22-4 LACTIC ACID 
• 64-19-7 acetic acid 
• 127-17-3 2-oxo-propionic acid 
• 51754-99-5 Methyl 3,5-O-Isopropylidene-β-D-xylofuranoside 
• 7045-40-1 Methyl 3,5-O-Isopropylidene-α-D-xylofuranoside 
• 15384-37-9 D-xylono-1,4-lactone 
• 6022-96-4 5-O-benzoyl-α-D-xylofuranose 
• 57884-47-6 (Z)-D-Arabinose-oxim 
• 57820-44-7 (E)-D-Arabinose oxime 
• 85051-62-3 (2R,3S,4S)-5-((Z)-3-{1-[(4,5-Diphenyl-oxazol-2-yl)-hydrazono]-ethyl}-phenylimino)-pentane-1,2,3,4-tetraol 

Relevant articles and documents

60CO-irradiation as an alternate method for sterilization of Penicillin G, neomycin, novobiocin, and dihydrostreptomycin

The effects of the use of 60Co-irradiation to sterilize antibiotics were evaluated. The antibiotic powders were only occasionally contaminated with microorganisms. The D-values of the products and environmental isolates were 0.028, 0.027, 0.015, 0.046, 0.15, 0.018, and 0.19 Mrads for Aspergillus species (UC 7297, 7298), A. fumigatus (UC 7299), Rhodotorula species (UC 7300), Penicillium oxalicum (UC 7269), Pseudomonas maltophilia (UC 6855), and a biological indicator microorganism, Bacillus pumilus spores (ATCC 27142). An irradiation dose of 1.14 Mrads, therefore, was sufficient to achieve a six-log cycle destruction of B. pumilus spores. Based on the bioburden data, a minimum irradiation dose of 1.05 Mrads was calculated to be sufficient to obtain a 10-6 probability of sterilizing the most radioresistant isolate, Pen. oxalicum. To determine the radiolytic degradation scheme and the stability of the antibiotics following irradiation, high-performance liquid chromatographic (HPLC) methods were developed. The resulting rates of degradation for the antibiotics were 0.6, 1.2, 2.3, and 0.95%/Mrad for penicillin G, neomycin, novobiocin, and dihydrostreptomycin, respectively. Furthermore, radiolytic degradation pathways for the antibiotics were identified and found to be similar to those commonly encountered when antibiotics are subjected to acidic, basic, hydrolytic, or oxidative treatments. No radiolytic compounds unique to 60Co-irradiation were found.

Synthesis, Radiosynthesis, and in vitro Studies on Novel Hypoxia PET Tracers Incorporating [18F]FDR

We report the synthesis of five radiotracers incorporating different oxyamine spacers between the hypoxia-reactive 2-nitroimidazole moiety and the 5-[18F]-fluorodeoxyribose ([18F]FDR, 12) prosthetic group: three linear alkyl chains w

Oleanane-type saponins and prosapogenins from Albizia julibrissin and their cytotoxic activities

Two undescribed oleanane-type saponins, julibrosides K–L, along with three undescribed oleanane-type prosapogenins, julibrosides M–O, were isolated from the stem bark of Albizia julibrissin Durazz. and the mild alkaline hydrolysate of the total saponin, r