3649-39-6 Usage
General Description
3-Benzylhypoxanthine is a chemical compound that belongs to the class of hypoxanthine derivatives. It is a purine analog with potential antineoplastic activity. 3-BENZYLHYPOXANTHINE inhibits the enzyme hypoxanthine-guanine phosphoribosyltransferase (HGPRT), which is involved in the salvage pathway of nucleotide biosynthesis, leading to the depletion of intracellular guanine nucleotides and subsequently inhibiting the proliferation of cancer cells. 3-Benzylhypoxanthine has been studied for its potential use in cancer treatment and has shown promise as a chemotherapeutic agent with potential anti-tumor activity.
Check Digit Verification of cas no
The CAS Registry Mumber 3649-39-6 includes 7 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 4 digits, 3,6,4 and 9 respectively; the second part has 2 digits, 3 and 9 respectively.
Calculate Digit Verification of CAS Registry Number 3649-39:
(6*3)+(5*6)+(4*4)+(3*9)+(2*3)+(1*9)=106
106 % 10 = 6
So 3649-39-6 is a valid CAS Registry Number.
InChI:InChI=1/C12H10N4O/c17-12-10-11(14-7-13-10)16(8-15-12)6-9-4-2-1-3-5-9/h1-5,7-8H,6H2,(H,13,14)
3649-39-6Relevant articles and documents
NOVEL HYPOXANTHINE AND THIOHYPOXANTHINE COMPOUNDS
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Page 18, (2010/02/08)
Disclosed are compounds of formula (I) wherein R3, R6, R8 are as described herein. The compounds are effective selective PDE IV inhibitors.
