365427-24-3

Basic information

• Product Name: 4-(3-Methoxyphenyl)-2-Methyl-1,3-thiazole
• Synonyms: 4-(3-Methoxyphenyl)-2-Methyl-1,3-thiazole;4-(3-METHOXYPHENYL)-2-METHYLTHIAZOLE
• CAS NO: 365427-24-3
• Molecular Formula: C₁₁H₁₁NOS
• Molecular Weight: 205.27614
• Mol File: 365427-24-3.mol
• Article Data: 5

Chemical Properties

• Appearance: /
• Storage Temp.: 2-8°C
• CAS DataBase Reference: 4-(3-Methoxyphenyl)-2-Methyl-1,3-thiazole(CAS DataBase Reference)
• NIST Chemistry Reference: 4-(3-Methoxyphenyl)-2-Methyl-1,3-thiazole(365427-24-3)
• EPA Substance Registry System: 4-(3-Methoxyphenyl)-2-Methyl-1,3-thiazole(365427-24-3)

Safety Data

• Hazardous Substances Data: 365427-24-3(Hazardous Substances Data)

Usage

General Description

4-(3-Methoxyphenyl)-2-Methyl-1,3-thiazole, also known as methoxyphenylthiazole, is a synthetic chemical compound with the molecular formula C11H11NOS. It is a heterocyclic compound containing a thiazole ring, and is commonly used in the pharmaceutical and agrochemical industries. Its properties and structure make it a versatile intermediate in the synthesis of various pharmaceuticals, including potential anticancer and antifungal agents. Additionally, it has been shown to have insecticidal and pesticidal activity, making it a valuable compound in the development of agricultural products. 4-(3-Methoxyphenyl)-2-Methyl-1,3-thiazole is a valuable building block for the development of diverse chemical compounds with potential applications in the fields of medicine and agriculture.

Upstream product

• 62-55-5 thioacetamide 
• 5000-65-7 2-bromo-3'-methoxyacetophenone 
• 122806-25-1 1-(3-methoxy-phenyl)-ethanone oxime 
• 108-24-7 acetic anhydride 
• 586-37-8 1-(3-Methoxyphenyl)ethanone 

Downstream Products

• 239448-53-4 4-(3-methoxyphenyl)-2-methyl-5-phenylthiazole 

Relevant articles and documents

Access to Thiazole via Copper-Catalyzed [3+1+1]-Type Condensation Reaction under Redox-Neutral Conditions

A new strategy for thiazoles via copper-catalyzed [3+1+1]-type condensation reaction from oximes, anhydrides and potassiumthiocyanate (KSCN) is developed herein. The transformation has good functional group tolerance and various thiazoles were formed smoothly in good to excellent yields under mild reaction conditions. This process involves copper-catalyzed N-O/C-S bond cleavages, activation of vinyl sp2 C-H bond, and C-S/C-N bond formations which are under redox-neutral conditions as well as operational simplicity.

Aryl and heteroaryl sulfonates

The invention relates to novel aryl and heteroaryl sulfonates of formula (Ia) and to methods for producing them and to novel aryl and heteroaryl sulfonates of formula (I) for treating and/or preventing diseases, especially for treating pain and neurodegen

An efficient synthesis of phenanthro-fused thiazoles by a non-phenolic oxidative coupling procedure of 4,5-diarylthiazoles

A concise synthesis of the title compounds 6 is accomplished in high overall yield in a two step process starting from bromoketone 4. A thiazole ring formation and a non-phenolic oxidative coupling reaction using PIFA are features of the described synthesis. An exploration of the electronic requirements and the regioselectivity of the cyclization is also presented.