365427-36-7

Basic information

• Product Name: 3-(dimethylamino)phenyl trifluoromethanesulfonate
• Synonyms: 3-(dimethylamino)phenyl trifluoromethanesulfonate
• CAS NO: 365427-36-7
• Molecular Weight: 269.245
• Mol File: 365427-36-7.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: 3-(dimethylamino)phenyl trifluoromethanesulfonate(CAS DataBase Reference)
• NIST Chemistry Reference: 3-(dimethylamino)phenyl trifluoromethanesulfonate(365427-36-7)
• EPA Substance Registry System: 3-(dimethylamino)phenyl trifluoromethanesulfonate(365427-36-7)

Safety Data

• Hazardous Substances Data: 365427-36-7(Hazardous Substances Data)

Upstream product

• 358-23-6 trifluoromethylsulfonic anhydride 
• 99-07-0 3-Dimethylaminophenol 

Downstream Products

• 1005759-17-0 2-(3-(N,N-dimethylamino)phenyl)benzoxazole 
• 1005759-14-7 5-(3-N,N-dimethylaminophenyl)-2-n-propylthiazole 
• 54263-82-0 3-(dimethylamino)benzoyl chloride 
• 16518-64-2 3-(dimethylamino)benzoic acid methyl ester 
• 2107-43-9 N,N-dimethyl 3-fluoroaniline 

Relevant articles and documents

Palladium-Catalyzed Chlorocarbonylation of Aryl (Pseudo)Halides Through In Situ Generation of Carbon Monoxide

An efficient palladium-catalyzed chlorocarbonylation of aryl (pseudo)halides that gives access to a wide range of carboxylic acid derivatives has been developed. The use of butyryl chloride as a combined CO and Cl source eludes the need for toxic, gaseous carbon monoxide, thus facilitating the synthesis of high-value products from readily available aryl (pseudo)halides. The combination of palladium(0), Xantphos, and an amine base is essential to promote this broadly applicable catalytic reaction. Overall, this reaction provides access to a great variety of carbonyl-containing products through in situ transformation of the generated aroyl chloride. Combined experimental and computational studies support a reaction mechanism involving in situ generation of CO.