365448-17-5

Basic information

• Product Name: C₁₂H₁₉ClOSiZn
• Synonyms: C₁₂H₁₉ClOSiZn
• CAS NO: 365448-17-5
• Molecular Weight: 308.211
• Mol File: 365448-17-5.mol
• Article Data: 4

Chemical Properties

• CAS DataBase Reference: C₁₂H₁₉ClOSiZn(CAS DataBase Reference)
• NIST Chemistry Reference: C₁₂H₁₉ClOSiZn(365448-17-5)
• EPA Substance Registry System: C₁₂H₁₉ClOSiZn(365448-17-5)

Safety Data

• Hazardous Substances Data: 365448-17-5(Hazardous Substances Data)

Upstream product

• 67963-68-2 t-butyldimethylsilyl-4-bromophenol 
• 7646-85-7 zinc(II) chloride 
• 126644-72-2 1-<(tert-butyldimethylsilyl)oxy>-4-chlorobenzene 

Downstream Products

• 1588767-91-2 (S)-2-(4-((tert-butyldimethylsilyl)oxy)phenyl)-2-fluoro-1,3-diphenylpropan-1-one 

Relevant articles and documents

Preparation of Polyfunctional Naphthyridines by Cobalt-Catalyzed Cross-Couplings of Halogenated Naphthyridines with Magnesium and Zinc Organometallics

CoCl2 (5%) catalyzes cross-couplings of various halogenated naphthyridines with alkyl- and arylmagnesium halides. Also, arylzinc halides undergo smooth cross-couplings with various naphthyridines in the presence of CoCl2·2LiCl (5%) a

Ligand-Free Copper-Catalyzed Negishi Coupling of Alkyl-, Aryl-, and Alkynylzinc Reagents with Heteroaryl Iodides

Reported herein is an unprecedented ligand-free copper-catalyzed cross-coupling of alkyl-, aryl-, and alkynylzinc reagents with heteroaryl iodides. The reaction proceeds at room temperature for the coupling of primary, secondary, and tertiary alkylzinc reagents with heteroaryl iodides without rearrangement. An elevated temperature (100 C) is required for aryl-heteroaryl and alkynyl-heteroaryl couplings.