36546-50-6

Basic information

• Product Name: Ethyl N-acetyl-L-tyrosinate hydrate
• Synonyms: Ac-Tyr-OEt H;N-Ac-Tyr-OEt·H2O;N-Ac-L-Tyr-OEt;N-Ac-L-Tyr-OEt·H2O;N-ACETYL-L-TYROSINE ETHYL ESTE&;Acetyl-L-tyrosine ethyl ester hydrate99%;N-Acetyl-L-tyrosine ethyleester monohydrate;ATEE
• CAS NO: 36546-50-6
• Molecular Formula: C13H19NO5
• Molecular Weight: 269.29
• EINECS: 212-663-5
• Product Categories: Amino Acids
• Mol File: 36546-50-6.mol
• Article Data: 0

Chemical Properties

• Melting Point: 80-81 °C(lit.)
• Boiling Point: 464.4 °C at 760 mmHg
• Flash Point: 234.7 °C
• Appearance: White/Crystalline Powder
• Density: 1.179 g/cm3
• Vapor Pressure: 3.03E-09mmHg at 25°C
• Storage Temp.: 2-8°C
• Solubility: soluble in Methanol
• Sensitive: Hygroscopic
• BRN: 2217900
• CAS DataBase Reference: Ethyl N-acetyl-L-tyrosinate hydrate(CAS DataBase Reference)
• NIST Chemistry Reference: Ethyl N-acetyl-L-tyrosinate hydrate(36546-50-6)
• EPA Substance Registry System: Ethyl N-acetyl-L-tyrosinate hydrate(36546-50-6)

Safety Data

• Hazard Codes: Xi
• Statements: 36/37/38
• Safety Statements: 24/25-36-26
• WGK Germany: 3
• F: 10-21
• TSCA: Yes
• Hazardous Substances Data: 36546-50-6(Hazardous Substances Data)

Usage

Description

Ethyl N-acetyl-L-tyrosinate hydrate is a chemical compound derived from the esterification of N-acetyl-L-tyrosine with ethanol. It is a white crystalline solid that is soluble in water and has a molecular weight of approximately 247.25 g/mol. Ethyl N-acetyl-L-tyrosinate hydrate is known for its potential applications in various fields, particularly in the pharmaceutical and chemical industries.

Uses

Used in Pharmaceutical Industry:
Ethyl N-acetyl-L-tyrosinate hydrate is used as a substrate in transesterification reactions with 1 M propan-1-ol, catalyzed by Carlsberg protease protein-coated microcrystals (PCMC). This application is crucial for testing the performance of subtilisin Carlsberg protein-coated microcrystals (PCMC) as a substrate for cross-linked crystals (CLECs) of subtilisin activity screening.
Additionally, Ethyl N-acetyl-L-tyrosinate hydrate can be used in the synthesis of various pharmaceutical compounds, such as drugs and drug intermediates, due to its unique chemical properties and reactivity.
Used in Chemical Industry:
In the chemical industry, Ethyl N-acetyl-L-tyrosinate hydrate can be employed as a building block or intermediate in the synthesis of various organic compounds, including specialty chemicals, agrochemicals, and other fine chemicals. Its versatility in chemical reactions makes it a valuable component in the development of new chemical products and processes.

Biochem/physiol Actions

N-Acetyl-L-tyrosine ethyl ester is an N-terminal and C-terminal protected L-tyrosine that is used in crosslinking studies and as a substrate for the detection, differentiation and/or characterization various proteases and esterases.

InChI:InChI=1/C13H17NO4.H2O/c1-3-18-13(17)12(14-9(2)15)8-10-4-6-11(16)7-5-10;/h4-7,12,16H,3,8H2,1-2H3,(H,14,15);1H2/t12-;/m0./s1