36556-53-3

Basic information

• Product Name: 2,3-dichloro-4-fluoroacetanilide
• CAS NO: 36556-53-3
• Molecular Weight: 222.046
• Mol File: 36556-53-3.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 2,3-dichloro-4-fluoroacetanilide(CAS DataBase Reference)
• NIST Chemistry Reference: 2,3-dichloro-4-fluoroacetanilide(36556-53-3)
• EPA Substance Registry System: 2,3-dichloro-4-fluoroacetanilide(36556-53-3)

Safety Data

• Hazardous Substances Data: 36556-53-3(Hazardous Substances Data)

Upstream product

• 351-83-7 4'-fluoroacetanilide 

Relevant articles and documents

Complementary Site-Selective Halogenation of Nitrogen-Containing (Hetero)Aromatics with Superacids

Site-selective functionalization of arenes that is complementary to classical aromatic substitution reactions remains a long-standing quest in organic synthesis. Exploiting the generation of halenium ion through oxidative process and the protonation of the nitrogen containing function in HF/SbF5, the chlorination and iodination of classically inert Csp2?H bonds of aromatic amines occurs. Furthermore, the superacid-promoted (poly)protonation of the molecules acts as a protection, favoring the late-stage selective halogenation of natural alkaloids and active pharmaceutical ingredients.